Oral
2025 Unmet Needs Challenge
ISMRM & ISMRT Annual Meeting & Exhibition • 10-15 May 2025 • Honolulu, Hawai'i
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Introduction |
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| 13:36 |
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5420. Potential
use of iTB Maps to Distinguish GBM Recurrence from
Pseudoprogression Based on Performance in the Context of Tumor
Infiltration
R. Wujek, M. Prah, M. Al-Gizawiy, K. Schmainda
The Medical College of Wisconsin, Milwaukee, United States
Impact: The validation of iTB maps the context of tumor
infiltration and in terms of the unmet need required
features indicate that a similar approach may be utilized to
distinguish glioblastoma recurrence from pseudoprogression.
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| 13:48 |
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5421. Application
of MRI histogram analysis based on non-Gaussian diffusion model
in distinguishing recurrence from pseudoprogression
Y. Zhang, P. Wang, E. Gao, K. Zhao, T. Chen, X. Ma, Y.
Zhang, J. Cheng
The First Affiliated Hospital of Zhengzhou University, ZhengZhou, China
Impact: Non-Gaussian diffusion MRI detects occult tumor
infiltration in peritumoral edema (invisible on conventional
MRI), enhancing recurrence/pseudoprogression prediction to
optimize GBM surgical and adjuvant therapy.
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| 14:00 |
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5422. A
Quantitative Relaxation Mapping Protocol Standardized by MR
Fingerprinting for Clinical Research in White Matter
Hyperintensity
G. Zhao, L. Sun, M. Wang, M. Nittka, J. Cheng, Y. Zhang
The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
Impact: Our study demonstrated the ability of MRF in
identifying WMH. This technology could solve the high
heterogeneity problem of existing image acquisition
differences, make it possible to accurately evaluate
automatic quantification algorithms, and promote the
diagnosis or evaluation across centers.
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| 14:12 |
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5423. Fetal
MR Thermometry Using Diffusion MRI.
N. Elsaid, K. Kapse, N. Andescavage, C. Limperopoulos
Children's National Hospital, Washington, United States
Impact: We implemented a method to directly compute the
average fetal temperature from the CSF and the amniotic
fluid diffusivity to measure the absolute fetal temperature.
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| 14:24 |
5424. Evaluating
MR-visible catheters for radiation-free cardiac catheterization
(9001)
M. Farooq, A. Farooq
Medical College of Georgia, Augusta, United States
Impact: This work identifies the most promising
MR-visible catheter technologies and highlights remaining
safety and workflow barriers. It will guide future
development toward radiation-free cardiac interventions,
with direct implications for pediatric and congenital heart
disease populations requiring repeated procedures.
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| 14:36 |
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5425. Progress
Towards a 136 mT Portable MRI for Neuropathological Assessment
in Preterm Neonates
M. Śliwiak, S. Altman, A. Purchase, J. Short, D. Gupta, Z.
Xiong, M. Davids, V. Klein, C. Jaimes, S. Bates, J.
Stockmann, L. Wald, C. Zimmerman Cooley
A.A. Martinos Center for Biomedical Engineering, Massachusetts General Hospital, Charlestown, United States
Impact: The 136 mT portable MRI system could transform
premature neonatal brain imaging by enabling rapid diagnosis
of ischemic and hemorrhagic abnormalities like GM-IVH,
facilitating earlier prognosis and neuroprotective
interventions and ultimately improving clinical outcomes
through enhanced early imaging capabilities.
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| 14:48 |
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5426. Toward
Robust Fat-Suppressed Gadolinium-Enhanced MRI Near Metal
Implants: A Local B₀ Shim Coil Insert Approach
Z. Long, H-J Yang, N. Binesh, A. Malagi, Y. Shang, L-t
Huang, J. Zepeda, F. Serry, D. Li, H. Han
Cedars-Sinai Medical Center, Los Angeles, United States
Impact: This hardware-based local B₀ shim approach can
transform musculoskeletal MRI near metal implants by
enabling uniform fat suppression and clarifying
gadolinium-enhanced lesions, thus improving clinical
diagnoses. Future investigations may expand this strategy to
broader anatomies and more severe off-resonance scenarios.
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| 15:00 |
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5427. Diffusion-presatured
STIR for fat suppression during Gadolinium-enhanced MRI at the
presence of metal implants
K. Jordanova, B. Hargreaves
Stanford University, Stanford, United States
Impact: A new diffusion-presaturated inversion recovery
sequence enables contrast-enhanced imaging with fat
suppression near metal within a single scan. This technique
could replace subtraction of pre- and post-contrast images
for fat suppression in applications such as cancer detection
near metal.
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| 15:12 |
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5428. Application
of an IEC 62464-1 MR Image Quality System for Standard Quality
Assurance in Fat-Suppressed MRI near Metallic Implants
L. Schuelert, A. Eger, D. Kokorin, G. Schaefers, A. Melzer
Innovation Center Computer Assisted Surgery (ICCAS), Institute at the Medical Faculty, Leipzig University, Leipzig, Germany
Impact: The use of the IEC standard is expected to
deliver a generalised approach ensuring the best data
quality in fat-suppressed Gd-based MRI in presence of
metals.
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| 15:24 | Discussion |
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