ISMRM25 - Now, in Some Time or Never: Is This Ready To Go Clinical? Neurofluids

ISMRM & ISMRT Annual Meeting & Exhibition • 10-15 May 2025 • Honolulu, Hawai'i

Now, in Some Time or Never: Is This Ready To Go Clinical? Neurofluids

Sunrise Course

ORGANIZERS: Seung Hong Choi, Harpreet Hyare, Christin Sander, Katharina Schregel, Wietske van der Zwaag

Tuesday, 13 May 2025

311

07:00 - 08:00

Moderators: Shinji Naganawa & Toshiaki Taoka

Skill Level: Basic to Intermediate

Session Number: S-T-05

CME Credit

Session Number: S-T-05

Overview
Advanced MRI methods to assess neurofluid flow and dynamics or proteins and metabolites are emerging and scientifically well investigated. Moreover, techniques to dramatically speed up image acquisition were developed. However, are these scientific achievements ready for the clinical routine? Which advancement is really needed for patient care? Will a novel technique make the clinician's life easier or just more complicated?

Target Audience
Neuroscientists, neuroradiologists, clinicians who currently explore new MRI techniques, and MR physicists and engineers developing new MRI methodologies.
Clinicians in search of a solution to a specific clinical problem, scientists that want to know if a specific application is transferable to the clinical routine soon, in the hopefully near future or at all.

Educational Objectives
As a result of attending this course, participants should be able to:
• Describe methods to image neurofluids;
• Identify fast imaging techniques that are applicable in the clinical routine; and
• Interpret the results from CEST-imaging in the context of brain diseases.

07:00		Ways to Image Neurofluids View Presentation Video Lynne Bilston Impact: Interest in using MR imaging to probe the anatomy, movement, and function of neurofluids has exploded in recent years. This talk will outline the key methods used, along with what parts of the neurofluid system they give insight into.
07:30		Which Neurofluids Do I Need To Image in My Patients? Junko Kikuta Impact: We comprehensively need to use MRI techniques (e.g., T2, CEST, diffusion MRI, and IV-GBCA) to evaluate ISF movement in the brain parenchyma and the fluid dynamics in the perivascular and subarachnoid spaces, as well as the parasagittal dura and meningeal lymphatics in patients.