ISMRM25 - Physical Chemistry Approaches for Contrast Mechanisms III

ISMRM & ISMRT Annual Meeting & Exhibition • 10-15 May 2025 • Honolulu, Hawai'i

Physical Chemistry Approaches for Contrast Mechanisms III

Sunrise Course

ORGANIZERS: Laura Bell, Shaihan Malik, Marco Palombo, Cristian Tejos

Wednesday, 14 May 2025

316C

07:00 - 08:00

Moderators: Jeremy Gordon & Gulin Oz

Skill Level: Intermediate to Advanced

Session Number: S-W-06

No CME/CE Credit

Session Number: S-W-06

Overview
The rich history of MRI is marked by techniques evolving from physical chemistry, encompassing, for example, spectroscopy, diffusion, exchange, and quantum filters. This session delves into the contemporary landscape of NMR physical chemistry, exploring untapped methods for integration into MRI scanners. Addressing the shift from in vitro to in vivo applications, practical considerations will be explored. Furthermore, variations in hardware performance will be considered, shedding light on factors influencing the translation of innovative methods into successful MRI applications.

Target Audience
Scientists interested in pushing the boundaries of MR contrasts, aiming toward translating novel techniques from other fields (e.g. chemical-physics) to tissue microstructure imaging.

Educational Objectives
As a result of attending this course, participants should be able to:
• List advanced NMR methods and their Integration into medical applications of MRI;
• Describe how transitioning from in vitro to in vivo applications in NMR and MRI happens; and
• Evaluate hardware performance and its impact on NMR-MRI method translation.

07:00		Probing Chemical Exchange Rates Using Hyperpolarized MR Matthew Merritt
07:30		Biological Applications of Exotic Spectroscopy Methods View Presentation Video André Döring Impact: This presentation covers advanced "exotic" Magnetic Resonance Spectroscopy (MRS) methods. It details techniques like edited MRS, diffusion-weighted MRS, and MRSI, highlighting their use in neuro-oncology, and studying neuroinflammation.