ISMRM & ISMRT Annual Meeting & Exhibition • 10-15 May 2025 • Honolulu, Hawai'i
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5262. Effect
of blood rheology and hematocrit on the estimation of
hemodynamic parameters in hypertrophic cardiomyopathy
J. Sotelo, H. Mella, F. Galarce, C. Velasquez, S. Uribe, T.
Sekine, E. Castillo
Universidad Técnica Federico Santa María, Santiago, Chile
Impact: This study shows the impact of incorporating
nonlinear blood viscosity models in the estimation of
hemodynamic parameters from 4D flow MR imaging in patients
with hypertrophic cardiomyopathy. Variable viscosity model
produces significant differences in diastolic phase.
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5263. WITHDRAWN | ||
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5264. Cardiac
CEST-MRI reveals early biochemical changes in transgenic models
of early mitochondrial dysfunction and hypertrophic
cardiomyopathy
J. Weigand-Whittier, T. Thottakara, M. Velasquez, M.
Wendland, M. R. Abraham, M. Vandsburger
UC Berkeley, Berkeley, United States
Impact: Early biochemical changes associated with
hypertrophic cardiomyopathy are currently undetectable with
conventional imaging. CEST-MRI and associated CEST contrasts
allow for these changes to be detected and studied.
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5265. Left
ventricular remodeling index predicts ventricular
tachyarrhythmia in dilated cardiomyopathy with ejection fraction
<35%
X. Jia, X. Chen, S. Zhao
Fuwai Hospital, National Center for Cardiovascular Diseases of China, Chinese Academy of Medical Sci, Beijing, China
Impact: CMR-derived LVRI is associated with VTA in
patients with nonischemic DCM with LVEF <35%, which may have
clinical significance in guiding future implantable
cardioverter-defibrillator implantation and improving risk
stratification for DCM patients with LVEF <35%.
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5266. Simultaneous
3-D adiabatic T1rho and quantitative susceptibility mapping for
characterization of myocardial infarction in ex vivo mouse
I. Räty, O. Nykänen, S. Laidinen, A-K Ruotsalainen, M.
Nissi, E. Ylä-Herttuala
A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland
Impact: This
study presents a simultaneous T1ρ and
QSM measurement for ex vivo assessment of myocardium after
factitious myocardial infarction in mice. The method allowed
determination of myocardial infarction based on co-localized
3-D T1ρ relaxation
time and quantitative susceptibility maps.
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5267. Single-Sequence
One-Stop Ferumoxytol-Enhanced Vascular Lumen and Wall Imaging
(SSO-FE-VLWI) for Comprehensive Cardiovascular Assessment
G. Si, G. Wu, P. Wang, J. Wei, C. Tian, P-Y Wu, P. Han, D.
Mu, M. Zhou, N. Gu
Southeast University, Nanjing, China
Impact: SSO-FE-VLWI provides a time-efficient approach
for comprehensive vascular evaluation, reducing the need for
additional sequences and improving clinical workflow.
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5268. Study
on the Differential Diagnostic Value of Cardiac Magnetic
Resonance Multiparametric Imaging for Atypical CA and
Compensated HHD
L. Tang, F. Wang, L. Yang, X. Yue
Ningxia Hui Autonomous Region People's Hospital, Yinchuan, China
Impact: This study quantitatively evaluates atypical CA
and HHD using T1 mapping and CMR-FT, providing imaging
evidence for diagnosis and supporting precision treatment.
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5269. Investigation
of cardiac-rhythm related differences in hemodynamics using a 3D
universal left atrial coordinate system dedicated to 4D Flow MRI
M. Sigovan, S. Boccalini, M. Beghella, V. Wang, A. Elsayed,
M. Nash, N. Duchateau, P. Douek, P. Chevalier
University of Lyon, CNRS, CREATIS Laboratory, Lyon, France
Impact: The volumetric universal coordinate system for
the left atrium enabled straightforward comparisons of blood
flow parameters between subjects. The method may prove
valuable in larger populations studies to highlight
pathology specific flow patterns and identify individuals
with significantly different patterns.
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5270. The
clinical value of native T1 and systolic-to-diastolic myocardial
volume ratio in evaluating hypertrophic cardiomyopathy
H. Wu, P. Liu, J. Lian
The First Afliated Hospital of Harbin Medical University, Harbin , China
Impact: The combined use of MVs/MVd and Native T1 could
be a novel indicator of myocardial function without the need
for contrast agents, has the potential to differentiate HCM
from the control group, as well as distinguish between
subgroups of HCM.
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5271. Quantitative
Assessment of Post-Valvular Mechanical Energy in BAV with Aortic
Lesions and Preserved Ejection Fraction on LV Workload
S. Aliabadi, J. Garcia
University of Calgary, Calgary, Canada
Impact: This study demonstrates that post-valvular peak
systolic integrated kinetic energy (KE) could serve as a
non-invasive marker of LV workload, supporting early
intervention strategies for improved risk stratification in
diverse BAV patient profiles.
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5272. Incremental
Value of Multiparametric Cardiac MRI for Non-invasive
Identification of Significant Acute Cardiac Allograft Rejection
P. Zhou
Fuwai Hospital, Beijing, China
Impact: Global longitudinal strain should be considered
in future prospective clinical trials for identifying
significant acute cardiac allograft rejection in heart
transplantation recipients.
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5273. Multiparametric
cardiac magnetic resonance to identify early myocardial
involvement in LGE negative light-chain amyloidosis
H. Zhu, H. j. Li
Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, Wu han, China
Impact: This study demonstrated that multiparametic CMR
can identify early myocardial involvement in patients with
AL amyloidosis, and all strain metrics show significant
associations with the markers of myocardial amyloid burden.
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5274. Single
breath-hold EPI-based 3D Late Gadolinium Enhancement Imaging
O. Goldman, K-P Kunze, J. Whitaker, R. Neji
King's College London, London, United Kingdom
Impact: Using EPI readouts for LGE-MRI allows 3D images
to be acquired in one breath-hold, with less undersampling
than previously proposed methods. Further developments to
the reconstruction could improve the resolution, to match
what can be realised in longer, free-breathing acquisitions.
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5275. Interpretable
Machine Learning Model for Characterizing Hemodynamic Biomarkers
in Bicuspid Aortic Valve induced Aortic Dilation
P. Franco, J. Sotelo, A. Guala, L. Dux-Santoy, J.
Garrido-Oliver, A. Evangelista, J. Rodríguez-Palomares
Universidad Andrés Bello, Santiago, Chile
Impact: This study advances the understanding of
hemodynamic changes in bicuspid aortic valve patients,
offering clinically relevant biomarkers for aortic dilation.
These insights could significantly enhance risk assessment,
guiding tailored interventions and improving patient
outcomes in cardiovascular care and management.
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5276. Cardiac
magnetic resonance and genetics in pediatric heart failure with
non-ischemia: prognostic implications
X. Gao, J. Lian, H. Wang, X. Lei
Beijing Anzhen Hospital, Capital Medical University, Beijing, China
Impact: The study demonstrated the common genetic
abnormalities in paediatric heart failure with non-ischemia
and also reveal some relationship between genetics and late
gadolinium enhancement. Cardiac magnetic resonance could
provide valuable predictive information for pediatric heart
failure with non-ischemia.
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