ISMRM & ISMRT Annual Meeting & Exhibition • 10-15 May 2025 • Honolulu, Hawai'i
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4954. Reproducibility
of MRI-based PDFF Quantification of Liver, Pancreas, Kidney, and
Paraspinal Muscle on MRI at 5 T and 3 T in NAFLD subjects
Y. Li, H. Yuan
Peking University Third Hospital, Beijing, China
Impact: 5.0 T is a reliable noninvasive biomarker of
PDFF measurements in abdominal organs and may be helpful for
early screening of NAFLD diseases.
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4955. Diffusion
Tensor Imaging Visualizes the Orientations of Muscle Bundles in
Isolated Smooth Muscle Layers of the Colon
M. YAMAGUCHI, K. Ikeda, S. Isono, Y. Machii, M. Akatsuka, Y.
Yamashita, Y. Muramatsu, H. Kanazawa, M. Ito, H. Kusahara,
T. Kobayashi
National Cancer Center Hospital East, Kashiwa, Japan
Impact: Our study results suggest a different approach
from the conventional image-histology correlation to
investigate smooth muscle layers in the digestive tract that
might provide microenvironment closely relevant to cancer
invasion in the gastro-intestinal organs.
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4956. Quantification
of the Proton Density Fat Fraction and Iron Content: A
Comparative Study Between 3.0 T and 5.0 T MRI
Y. Li, H. Yuan
Peking University Third Hospital, Beijing, China
Impact: Due to high interfield agreement of the PDFF and
R2* with 3.0 T, 5.0 T could be used as a reliable
noninvasive biomarker for quantifying fat and iron contents.
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4957. Non-Invasive
Visualisation of the Anteromedial and Posterolateral Bundles of
the ACL In-Vivo using Virtual Arthroscopy
H. Lanz, K. Chappell, M. Ristic, J. McGinley, C. Gupte, D.
Amiras
Imperial College London, Frome, United Kingdom
Impact: Our methodology enables non-invasive
visualisation of the ACL microstructure in-vivo. Successful
differentiation of the anteromedial and posterolateral ACL
bundles establishes a lower bound of accuracy. ACL damage
can now be assessed in upcoming patient trials with known
accuracy.
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4958. Highly
Sensitive Padded Coil Design using AIR™ Technology for 3T Spine
and Body Imaging
Y-J Stickle, C. Follante, M. Giancola, F. Robb, T. Stickle,
V. Taracila, K. Barnhart, K. Calderwood, M. Fung, Y. Wen, E.
T. Tan, A. Lowe, D. B. Sneag
GE Healthcare, Aurora, United States
Impact: This conformal, padded posterior array design
accommodates higher acceleration and SNR for in-vivo 3T
spine and body imaging.
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4959. Quantitative
UTE MRI T2* Mapping for Detecting Partial ACL Injuries: A Pilot
Study
M. Rothe, O. Hensel, K. Bohndorf, R. Brill, W. Wohlgemuth,
A. Gussew
University Hospital Halle (Saale), Halle (Saale), Germany
Impact: UTE MRI T2*-mapping offers a non-invasive method
for detecting partial ACL tears, which are often missed by
traditional imaging. This technique could enhance early
diagnosis, guide treatment decisions, and improve patient
outcomes in ligament injury management.
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4960. Noninvasive
MR Lymphangiography for assessing lymph fluid congestion in
human lymphedema
M. Aumann, S. Taylor, V. Crain, M. Garza, A. Scott, M.
Darrington, M. Pridmore, A. Brown, Y. Luo, P. Donahue, R.
Crescenzi
Vanderbilt University Medical Center, Nashville, United States
Impact: Noninvasive MR lymphangiography can be applied
in clinically-feasible scan time, and may provide useful
imaging biomarkers in assessing severity of edema in
lymphedema and lymphatic functioning, which could be used to
more deeply characterize lymphedema development and novel
therapies.
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4961. Clinical
Utility of FDG PET/MRI in Detection of Pain Generators in
Patients with Chronic Pain
F. Rashidi, R. do Vale Souza, S. Biswal, A. Pirasteh
University of Wisconsin–Madison, Madison, United States
Impact: FDG PET/MRI is a promising tool in management of
patients with chronic pain among whom the origin of pain
remains unknown. Further validation through larger
multi-center studies with appropriate controls are needed
before widespread implementation.
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4962. High-Impedance
Wireless Coax Coil for Enhanced Wearable MRI Applications
E. Xiao, S. Hayat, W. Liao, P. He, N. Li, F. Du, W. Cao, X.
Zhang, Q. Chen, Y. Li
Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China
Impact: This design is ideal for imaging small, curved
body parts, improving comfort and efficiency in wearable
MRI.
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4963. Variations
in skeletal muscle T2, water and proton density fat fraction in
patients with chronic kidney disease: a preliminary analysis
S. Lin, J. Jeong, J. De Carvalho, F. Kamal, J. Park, D.
Reiter
Emory University, Atlanta, United States
Impact: Validating T2,
water and PDFF as biomarkers for CKD-related myopathy
could enable earlier detection and targeted intervention,
potentially reducing the risk of adverse cardiovascular
outcomes and improving patient prognosis.
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4964. Contribution
of MRI to the forensic reconstruction after claimed survived
strangulation
I. KLASINC, T. Widek
D&F Institute of Forensic Medicine, Medical University of Graz, Graz, Austria
Impact: MRI allows to diagnose survived strangulation
with a high sensitivity and specificity and adds important
information on the attack itself. Native MR scan of the neck
in cases of reported manual strangulation therefore
contributes to the forensic reconstruction.
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4965. Robust
T2 Mapping in the Presence of Large B1+ Inhomogeneities
M. Keerthivasan, M. Bruno, J. Fritz, I. Khodarahmi
Siemens Medical Solutions USA Inc, New York, United States
Impact: The use of a B1+ sensitized TSE sequence to
estimate T2 relaxometry can improve estimation performance
in areas of large B1+ inhomogeneities near metallic
implants. This would allow quantitative assessment and
characterization of bone pathology near the arthroplastic
implant interface.
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4966. Self-decoupled
Wireless array for SNR enhancement in 5T MRI
W. Liao, E. Xiao, W. Cao, F. Du, N. Li, L. Chao, X. Zhang,
Q. Chen, Y. Li
Southern University of Science and Technology , Shenzhen, China
Impact: This work promises better MRI image quality and
potential broader applications in MRI.
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4967. 3D
T2* Mapping of the Medial Meniscus at 7T Before and After
Posterior Root Tear Repair: A Pilot Study
A. W. Kajabi, K. Knutsen, E. Hedayati, C. Steinberger, A.
Lamba, S. Zbyn, J. Smith, L. Tollefson, G. Metzger, R.
LaPrade, J. Ellermann
University of Minnesota, Minneapolis, United States
Impact: This study utilizes the high signal-to-noise
ratio of 7 Tesla and 3D T2* mapping to quantitatively and
longitudinally assess meniscal tissue integrity in patients
following medial meniscus posterior root tear repair,
providing valuable insights into the effectiveness of the
intervention.
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4968. WITHDRAWN | ||
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4969. Knee
Imaging at 0.05 T with Deep Learning Superresolution
Reconstruction
Y. Ding, V. Lau, S. Su, X. Li, J. Hu, J. Zhang, X. Lin, L.
Wu, A. Lin, A. Leong, Y. Zhao, E. Wu
The University of Hong Kong, Hong Kong, Hong Kong
Impact: The method effectively overcomes the low-signal
barrier, reconstructing fine anatomical structures at 0.05
Tesla that are reproducible within subjects and consistent
across two protocols. It enables rapid, high-quality ULF MRI
for potential point-of-care applications.
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