ISMRM & ISMRT Annual Meeting & Exhibition • 10-15 May 2025 • Honolulu, Hawai'i

ISMRM & ISMRT 2025 Annual Meeting & Exhibition

Traditional Poster

Vascular Imaging in Stroke

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Vascular Imaging in Stroke
Traditional Poster
Tuesday, 13 May 2025
Building:   Room: Exhibition Hall
14:30 -  15:30
Session Number: T-21
No CME/CE Credit

  5048. Prediction of aneurysm thrombosis after flow diverter stent treatment using four-dimensional flow MRI technique
M. Morikawa, H. Koike, H. Ishimaru, R. Toya, Y. Morofuji, T. Matsuo
Nagasaki University Hospiral, Nagasaki, Japan
Impact: 4D flow MRI predicts future aneurysm thrombosis after FDS implantation.
  5049. Dynamic Observation of Neuroprotective Effect of rTMS on BBB in an Ischemic Stroke Rat Model using DCE-MRI combined with Immunofluorescence
X. Tang, Q. Zhang, W. Liu, H. Shao, S. Huang, A. Saeed, C. Liu, F. Guo, L. Peng, W. Zhu
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Impact: This study demonstrates that rTMS can effectively reduce BBB permeability and infarct volume in ischemic stroke, suggesting a potential therapeutic approach to improve neurological outcomes by stabilizing the BBB.
  5050. Preliminary Findings from a Longitudinal Study on Intracranial Atherosclerotic Disease and Stroke Risk in Brain Tumor Patients
B. Sun, M. Hassan, M. Mosi, A. Safwat, C. Zhu, M. Mossa-basha
University of Washington, SEATTLE, United States
Impact: The incidence of AIS in brain tumor patients, albeit low, underscores the need for vigilant cardiovascular monitoring in this high-risk group.These findings highlight the importance of early detection and management of ICAD to mitigate stroke risk and improve patient outcomes.
  5051. Longitudinal Assessment of Whole-brain Perfusion in Mice with Transient Middle Cerebral Artery Occlusion by BOLD-DSC MRI
T. T. Le, G. H. Im, S-G Kim
Center for Neuroscience Imaging Research (CNIR), Institute for Basic Science (IBS), Suwon, Korea, Republic of
Impact: This study demonstrates the utility of BOLD-DSC MRI as a non-invasive, real-time approach to monitor hemodynamic changes in ischemic stroke, revealing both the immediate and prolonged effects of transient ischemia on CBV and CBF.
  5052. Optimizing Accelerated Protocols for Clinical T1w Vessel Wall Imaging: A Comparison of Deep Learning, Compressed Sensing, and CAIPI Methods
S. Pandey, M. Taso, R. Sellers, Z. Fan, K. Guggenberger, S. Lyo, C. Freeman, C. Zhu, J. Song, M. D. Tisdall
Perelman School of Medicine at the University of Pennsylvania, Philadelphia, United States
Impact: This study optimizes intracranial VWI using 3D T1w SPACE with DL, CS, and CAIPI for 20- and 64-channel coils, achieving reduced scan times. The 64-channel CS (6x) matched clinical image quality, while DL provided superior noise suppression on 20-channel coils.
  5053. Association between Hemodynamics and Plaque Distribution: Insights from 4D Flow Imaging of M1 Segment in Ischemic Stroke Patients
L. Liu, P. Jiang, P. Wu, Y. Xue, H. Wang, Z. Chen
Institute of Science and Technology for Brain-inspired Intelligence, Fudan University, Shanghai, China
Impact: Our findings enhance understanding of hemodynamics effect on plaque development in intracranial atherosclerosis, and may provide guidance for risk assessment and treatment strategies.
  5054. Full-automation of mapping perivascular space using DTI-ALPS – characterization using the moyamoya disease/syndrome
T-c Yeh, H-Y Wu, T-Y Chen, P-C Yu, C-M Cheng, C-C Chou
Taipei Veterans General Hospital, Taipei, Taiwan
Impact: DTI-ALPS detected the damage of PVS in moyamoya disease with infract, when DTI-ALPS was not able to detect the loss of PVS of arterial site in moyamoya disease without infarct.
  5055. Characterisation of compartmental diffusion and transverse relaxation properties of rat ischaemic tissue after stroke
E. Farrher, K-H Cho, C-W Chiang, S-M Huang, M-J Chen, C-H Choi, L-W Kuo, N. J. Shah
Forschungszentrum Jülich, Jülich, Germany
Impact: The application of multi-echo NODDI to investigate microstructural properties of ischaemic tissue is enabled by releasing the intrinsic diffusivity (conventionally fixed to a brain-wide value), which is greatly affected in this tissue pathology.
  5056. Use of Mean Apparent Propagator (MAP) MRI in Patients with Acute Ischemic Stroke: A comparative study with DTI and NODDI
J. Diamandi, C. Raimondo, M. Alizadeh, K. Piper, P. Patel, A. Flanders, S. Tjoumakaris, R. Gooch, P. Jabbour, R. Rosenwasser, N. Mouchtouris
University of Pittsburgh School of Medicine, Pittsburgh, United States
Impact:
This study shows how the time-efficient MAP MRI has potential for clinical use in patients with
AIS. RTPP, PA, and RTOP MAP measures were closely related with ICVF, OCI, FWF NODDI
measures, and could serve as equivalent measures.
  5057. A Predictive Model for the Risk of Stroke in ICAS patients based on ASL and High-resolution MRI
L. Li, M. Tang, X. Yan, Y. Wen, K. Ai, X. Lei, X. Zhang
Shaanxi Provincial People's Hospital, xi an, China
Impact: The nomogram integrating plaque characteristics of HR-MRI with presence of 2.5s-ATA in ASL imaging can accurately predicts ischemic stroke in sICAS, supporting risk stratification for stroke decision-making. It also offers a foundation for early risk assessment and intervention in TIA.
  5058. Investigation of the glymphatic system associated with post-stroke fatigue utilizing diffusion tensor imaging along the perivascular space
P. Wang, Z. Lu, W. Sun, Y. Zhang
The First Affiliated Hospital of University of Science and Technology of China, Hefei, China
Impact: The glymphatic system function is closely related to the occurrence and progression of post-stroke fatigue, which may be a potential therapeutic target for the treatment and prevention of post-stroke fatigue. 
  5059. Predicting 12 Month Functional Recovery After Ischemic Stroke Using Lesional Topography-Based Deep Neural Network
J. Lee, C-W Kim, Y. Kim, J. Lee, D. Y. Kim, J. Y. Choi
Yonsei University, Wonju, Korea, Republic of
Impact: This study demonstrates that incorporating topographic features into predictive models provides additional information, significantly improving outcome predictions for ischemic stroke patients.
  5060. Potential of Intranasally Delivered Exosomes Derived from Mesenchymal Stem Cells as Treatment for Ischemic Stroke: Proton and Sodium MRI at 21.1 T
A. Arbabian, M. Elumalai, S. Grant
National High Magnetic Field Laboratory, Tallahassee, United States
Impact: MRI-based evaluation of intranasal EV therapy provides a reliable approach to monitor recovery and sodium dynamics post-stroke, meeting a critical need for non-invasive, effective treatments and their assessment.
  5061. A fast stroke imaging protocol at 0.5T using high performance gradients
W. Oakden, C. Harris, C. Wiens, J. Stainsby, S. Chavez, A. Curtis
Synaptive Medical , Toronto, Canada
Impact: A 0.5T head-only MRI equipped with high performance gradients can potentially be used for rapid diagnosis of acute stroke. The small footprint, low field, and head-only design makes this magnet easier to site, improving MRI access for acute stroke patients.
  5062. Kidney-brain crosstalk: early assessment of brain damage in chronic kidney disease by using brain microcirculation impariment features
X. Guo, A. Mei, J. Qu, X. Lou, J. Lyu
First Medical Center of Chinese PLA General Hospital, Beijing, China
Impact: WMH potentially serving as an early warning indicator of the severity of cerebral damage in kidney disease.
  5063. MRI Evaluation of Cerebral Microbleeds, Silent Infarct, Iron Deposit with QSM in Sickle Cell Disease and Thalassemia Compared to Healthy Controls
H. Yu, W. Lin, M-Y Su, H. Do, D. Berkeley, J. Soun, Y. Zhang, P. Chang, J-H Chen, B. Tymkiw, W. AlGhuraibawi, M. Kadbi, M. Fisher, Z. Pakbaz
University of California, Irvine, United States
Impact: Sickle cell and Thalassemia patients may need blood transfusions, which leads to iron overload. Brain iron may also increase due to microvasculature damage. QSM may be performed to evaluate iron deposit levels and microbleeds to help improve their precision care.
  5064. Prediction of Prognosis in Acute Ischemic Stroke Based on Multimodal MRI Radiomics and Deep Learning.
L. Pei, X. Han
Department of Radiology, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People’s Hospital, quzhou, China
Impact: These findings suggest that CRD model holds considerable potential for aiding clinicians in risk assessment and decision-making for AIS patients.
  5065. Hyperemia detection on dynamic susceptibility contrast versus arterial spin labeling MRI in stroke post-endovascular therapy
C. Lomahan, M. Luby, G. Kalarakis, A. Hsia, J. Lynch, S. Somani, F. Arnberg-Sandor, L. Latour
National Institutes of Health (NIH)/ National Institute of Neurological Disorders and Stroke (NINDS), Bethesda , United States
Impact: Hyperemia detection by arterial spin labeling-relative cerebral blood flow compared to dynamic susceptibility contrast-relative cerebral blood flow may be more accurate in evaluating blood flow increases which can contribute to optimization of clinical care for stroke patients post-EVT.
  5066. The Relationship Between LSA Morphological Characteristics and Stroke Occurrence at 7T
R. Li, J. Lv, J. Qu, X. Lou
The First Medical Center of Chinese PLA General, Beijing, China
Impact: 3D TOF MRA at 7T can achieve subtle imaging of LSA, and the number of LSA branches and LSA length can serve as potential imaging morphological characteristics for predicting stroke occurrence MCA stenosis patients.
  5067. Feasibility of multi-echo QSM to quantify cortical iron depositions hindering cognitive improvement in patients after carotid endarterectomy
M. Yabuki, Y. Akamatsu, I. Uwano, F. Mori, M. Sasaki, K. Yoshioka, K. Chida, M. Kobayashi, S. Fujiwara, K. Ogasawara
Department of Neurosurgery, School of Medicine,Iwate Medical University, Yahaba, Japan., Iwate prefecture, Japan
Impact: The present study demonstrated that preoperative high cortical magnetic susceptibility adversely affects cognitive improvement after CEA and that preoperative QSM predicts patients who will not experience cognitive improvement after CEA.
  5068. Intra-session repeatability of regional oxygen extraction fraction quantification using asymmetric spin echo MRI
A. Song, W. Richerson, M. Aumann, S. Davis, L. Milner, L. Jordan, M. Donahue
Vanderbilt University Medical Center, Nashville, United States
Impact: Region-wise modeling of asymmetric spin echo MRI data may provide precise measurement of oxygen extraction fraction, an important hemodynamic measure in cerebrovascular research. Findings from this study suggest potential sensitivity to subtle changes in regional hemo-metabolism with sickle cell disease.
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