ISMRM25 - Insights from Neuroimaging of CNS, Head & Neck Pathology

ISMRM & ISMRT Annual Meeting & Exhibition • 10-15 May 2025 • Honolulu, Hawai'i

Insights from Neuroimaging of CNS, Head & Neck Pathology

Traditional Poster

Tuesday, 13 May 2025

Building: Room: Exhibition Hall

13:30 - 14:30

Session Number: T-24

No CME/CE Credit

		5028. Enhanced Spinal Cord Lesion Detection in Multiple Sclerosis Using White-Matter-Nulled 3D MPRAGE with Deep Learning Reconstruction PDF Poster F. Munsch, A. Ravache, T. Yamamoto, B. Zhang, M. Lacoste, H. Fukutomi, T. Tourdias, V. Dousset University of Bordeaux, Bordeaux, France Impact: This study demonstrates that 3D WMn MPRAGE combined with deep learning reconstruction significantly improves spinal cord lesion detection in multiple sclerosis, offering superior contrast and fewer artifacts than conventional MRI, potentially enhancing early diagnosis and treatment outcomes.
		5029. Cross-modal deep learning to predict multiple sclerosis cervical spinal cord damage with digital monitoring of motor function PDF Poster P-J Lu, T. Woelfle, A. Cagol, M. Ocampo-Pineda, F. Spagnolo, Ó. Reyes, L. Melie-Garcia, M. Weigel, J. Kuhle, L. Kappos, J. Lorscheider, C. Granziera University Hospital and University of Basel, Basel, Switzerland Impact: The performance of the proposed cross-modal neural network indicates that smartphone walking tests correlate with structural changes in cervical spinal cord and might assist clinical assessments in multiple sclerosis.
		5030. Macrovascular contamination may confound partial volume correction in ASL-derived CBF maps in patients with cerebrovascular disease PDF Poster J. M. Sousa, T. Wettervik, J. Berglund, P. Enblad, A. Lewén, J. Wikström, M. Fahlström Uppsala University, Uppsala, Sweden Impact: The choice of macrovascular correction method can negatively impact CBF estimates, depending on the PVC approach used. Linear regression PVC demonstrated greater precision, both with and without macrovascular correction, compared to the Bayesian method
		5031. Metasurface Enabled In Vivo Cervical Spine Imaging at 7T PDF Poster P. Jacobs, N. Wilson, M. Elliott, R. Reddy University of Pennsylvania, Philadelphia, United States Impact: By utilizing a pair of inexpensive metasurfaces higher quality c-spine imaging can be accomplished at 7T without the need for dedicated RF coils.
		5032. Glymphatic System Alterations in Thyroid Eye Disease: Evidence from DTI-ALPS Analysis H. Zhang, M. Jiang, Y. Liu, X. N. Lee, Z. Fang, J. Li, Y. Li, J. Sun, X. Tao, X. Song, H. Zhou, X. Fan Department of Ophthalmology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Shanghai, China Impact: This study highlights the glymphatic system's potential role in TED-related brain changes, emphasizing the need for further exploration of its pathophysiological mechanisms. Future validation of these findings may open new avenues for understanding and managing neurological impacts in TED.
		5033. Spinal Cord T2* mapping with Multi-echo Radial Stack of Star Acquisition at 7T PDF Poster S. N. Adnani, T. Denney, R. Beyers, A. Bashir Auburn University Neuroimaging Center, Auburn, United States Impact: Imaging small-diameter structures such as the spinal cord at high spatial resolutions demands new data acquisition and processing techniques to mitigate limitations due to motion artifacts. Radial MRI acquisition can help reduce motion artifacts and increase speed.
		5034. Quantitative evaluation of spinal cord cine-MRI with optical flow analysis: comparison with phase contrast PDF Poster R. Iwasaki, T. Horie, M. Kawakubo, N. Konta, S. Takano, H. Atsumi, T. Niwa Tokai University Hospital, Kanagawa, Japan Impact: This approach holds potential for diagnosing and evaluating spinal conditions by providing quantitative insights into spinal cord motion. It could improve clinical decision-making for Chiari I malformation , aiding in assessing treatment efficacy and patient outcomes.
		5035. Evaluation of Publicly Available Deep Learning Lumbar Spine MRI Analysis Tool for Prioritizing MRI Evaluation PDF Poster N. Kurt, S. Akbas, R. Russo, S. Soman Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, United States Impact: The SpineNetV2 publicly available deep learning software has potential to serve as a prioritization tool for moderate to severe vertebral canal narrowing, which can aid in screening for patients with potentially critical spinal stenosis.
		5036. Habitat-based radiomics analysis utilizing Synthetic MRI for the prediction of lymph node metastasis in oral cancer R. Wang, Y. Zhang, J. Shi, Y. Yuan, X. Tao Shanghai Ninth People’s Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China Impact: This habitat-based radiomics model improves accuracy in predicting lymph node metastasis in oral cancer, aiding clinical decision-making and patient management.
		5037. Amide Proton Transfer-weighted MRI and DWI as Biomarkers for Predicting Tumor Grades in Head and Neck Squamous Cell Carcinoma H. Wei, F. Yang, X. Yu, L. Xie, M. Lin Department of Diagnostic Radiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China, Beijing, China Impact: APTw and ADC provide unique insights into tumor microenvironment. Incorporating these imaging modalities into clinical practice offers a non-invasive approach for tumor grading, which could enhance preoperative assessment and potentially improve patient management.
		5038. MRI Assessment of Intrinsic Neural Timescale and Gray Matter Volume in Duchenne muscular dystrophy PDF Poster X. Niu, H. Xu, Y. Guo, S. Zhang, B. Cheng, X. Cai Department of Radiology, West China Second University Hospital, Sichuan University, Chengdu, China Impact: This research provided a comprehensive DMD neurobiological profile. The identification of neurobiomarkers through advanced MRI techniques could facilitate early diagnosis of cognitive issues in DMD, guide personalized treatments, ultimately enhancing the quality of life for individuals with DMD.
		5039. Quantification of Total White Matter Perivascular Space Volume: Follow-up in Dutch-type Cerebral Amyloid Angiopathy PDF Poster M. Schipper, T. van Harten, A-T Razoux-Schultz, K. Kaushik, L. Hirschler, S. Voigt, I. Rasing, E. Koemans, R. van Dort, R. van der Zwet, S. Schriemer, E. van Zwet, J. van der Grond, M. van Buchem, S. Greenberg, M. Wermer, M. van Osch, M. van Walderveen, S. van Rooden Leiden University Medical Center, Leiden, Netherlands Impact: Sensitive measurement of PVS-enlargement will increase our understanding of disease mechanisms and allow monitoring of disease progression. This is relevant for developing treatment strategies and especially for tracking the effectiveness of treatments.
		5040. High Resolution Super-Resolved Structural FSE at Ultra-low Fields for Source Reconstruction in MEG J. Gholam, L. Tait, J. Benacek, S. Manolova, H. Statham, G. Perry, F. Padormo, M. Cercignani, K. Singh, D. Jones CUBRIC, School of Psychology, Cardiff University, Cardiff, United Kingdom Impact: MEG source localisation is significantly aided by knowledge of participant neuroanatomy. ULF-MRI offers accessible imaging to implanted populations, as well as providing nervous or younger participants clear lines-of-sight and freedom to be comforted by caregivers.
		5041. Optimizing MPPCA for Complex Sodium MRI: Component Analysis and Noise Characterization at 3T PDF Poster A. Das, Y-C Lin, Y. Qian New York University Grossman School of Medicine, New York, United States Impact: This comprehensive validation establishes MPPCA as a robust denoising method for complex sodium MRI, providing specific guidelines for component selection and quality metrics. The improved image quality enhances sodium MRI's potential for clinical applications in metabolic and neurological assessments.
		5042. Myelin Assessment in Neurodegeneration: Correlation of R1 Relaxation and Diamagnetic Susceptibility in White Matter Using χ-Separation PDF Poster M. Hori, K. Kamiya, J. Ebina, M. Kobayashi, S. Mizumura, H. Terada, K. Murata, J. Lee, O. Kano Toho University, Tokyo, Japan Impact: A novel methodχ-separation enables myelin assessment in neurodegenerative white matter, reducing iron's confounding effects. This method allows researchers to study myelin independently, potentially enhancing diagnostic precision in neurodegenerative disease Synopsis
		5043. Benefits and limitations of diffusion imaging at 7T with a high-performance gradient system: a comparative study with 3T PDF Poster H. Liang, S. Li, L. Nie, Y. Xiong, B. Xu, B. Wu GE HealthCare MR Research, Beijing, China Impact: This study enhances neuroimaging by demonstrating significant advantages and limitations of 7T diffusion imaging, informing future research and clinical applications in brain health assessment.
		5044. Oxygen-enhanced MRI of the brain using 3D VIBE and 3D MR fingerprinting PDF Poster Y. Fushimi, S. Okuchi, A. Sakata, T. Yamamoto, S. Otani, S. Nakajima, S. Ikeda, S. Ito, M. Umehana, Y. Ma, S. Morooka, J. Fujimoto, H. Imai, Y. Urushibata, Y. Nakamoto Kyoto University Graduate School of Medicine, Kyoto, Japan Impact: Oxygen-enhanced MRI (OE-MRI) utilizing 3D volumetric interpolated breath-hold examination (3D VIBE) can indicate rapid drainage from interstitial fluid (ISF) into cerebrospinal fluid (CSF) via intramural periarterial drainage (IPAD) pathway.
		5045. Application of high-resolution 3D vessel wall MRI (HR-3D-VW-MRI) in Primary Angiitis of the Central Nervous System PDF Poster H. Zhou, T. Li, X. Zhang, Y. Jiang, Y. Meng, S. Yin, Y. Wang Department of Radiology, the First Hospital of Jilin University, Changchun, China Impact: This study significantly improved the diagnostic accuracy of Primary Angiitis of the Central Nervous System (PACNS) and provided a new effective tool for monitoring disease progression by using high-resolution 3D-VW-MRI technology.
		5046. Causal associations between iron levels in subcortical brain regions and psychiatric disorders: a Mendelian randomization study PDF Poster W. Du, B. Tang, W. Zhang, S. Lui West China Hospital of Sichuan University, Chengdu, China Impact: The observed bidirectional trends between subcortical iron levels and psychiatric disorders, indicating the importance of the underlying biomechanical interactions between brain iron regulation and these disorders.
		5047. Simultaneous Dynamic Sodium (23Na) MRI and EEG Analysis of Cerebrospinal Fluid Flow Velocity in the Human Brain During Sleep PDF Poster Y-C Lin, K. Watson, X. Chen, S. Henin, N-M Kumbella, J. Quimbo, Y. Ge, A. Masurkar, A. Liu, Y. W. Lui, Y. Qian Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York Universi, New York, United States Impact: This work may clarify sleep’s role in Aβ clearance in humans.

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