ISMRM & ISMRT Annual Meeting & Exhibition • 10-15 May 2025 • Honolulu, Hawai'i

ISMRM & ISMRT 2025 Annual Meeting & Exhibition

Traditional Poster

Imaging Insights in the Brain: Brain Structure, Function & More

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Imaging Insights in the Brain: Brain Structure, Function & More
Traditional Poster
Monday, 12 May 2025
Building:   Room: Exhibition Hall
14:45 -  15:45
Session Number: T-27
No CME/CE Credit

  4875. Multi-Task Learning with Hierarchical Label Consolidation for Efficient and Accurate Brain MRI Segmentation of 169 Regions
P-C Chen, T-Y Huang, Y-R Lin, T-C Chuang, H-W Chung
National Taiwan University of Science and Technology, Taipei, Taiwan
Impact: The method enhances efficiency and accuracy in brain MRI segmentation, allowing integration of additional tasks like cortical thickness estimation, leading to a multifunctional open-source brain MRI processing toolbox.
  4876. Sex-based differences in cerebral cortical structural development: a comparison between preterm and full-term neonates
Y. Zhang, Y. Feng, S. Wang, M. Wang, X. Li, J. Yang
The First Affiliated Hospital of Xi'an Jiaotong University,, Xi'an, China
Impact: A better understanding of sex-related differences in healthy cerebral cortex structure during the neonatal period may help identify risk factors and protective mechanisms for brain disorders.
    4877. WITHDRAWN
  4878. Association of gray-white matter junction tissue volume loss with metabolic biomarkers in patients with type 2 diabetes
G-H Jahng, C-W Ryu, Y. Tian, S. Park, I-K Jeong
Kyung Hee University Hospital at Gangdong, Seoul, Korea, Republic of
Impact: This study contributes to the field of diabetes and neuroimaging by introducing the concept of gwJTV as a new MRI measure for evaluating brain tissue integrity in T2D patients. 
  4879. Potential association between cognitive impairment and pre-pregnancy Body mass index in women with preeclampsia
Y. Wang, X. Zhang, N. Wang, L. Yang, T. chen, L. Guo
Binzhou medical university, Yantai, China
Impact: Our findings suggest that the reduction of GMV volume in bilateral frontal and temporal lobes in PE patients can be used as a potential neuroimaging indicator of brain injury.
  4880. Brain iron alterations associated with metabolic syndrome in the UK Biobank study cohort
X. Zhang, N. Wang, Y. Gao, C. Sui, Z. Cheng, P. Liang, Y. Chen, J. Xin, L. Guo, C. Liang
Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China
Impact: Iron deposition in the brains of metabolic syndrome patients increases their susceptibility to brain damage and possibly degenerative diseases. Understanding this metabolic disturbance is crucial for managing brain iron levels in Mets patients as they age.
  4881. Comparison of the cortical thickness and gray matter volume alterations in Multiple system atrophy and Parkinson’s disease
J. Peng, P. Wang, Y. Bao, G. Fan, E. Wang, Y. Ya, Y. Jia, P. Wu
The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China, Suzhou, China
Impact: Our results enrich the knowledge of morphometric MRI difference in MSA and PD, might become potentially useful imaging biomarkers for differential diagnosis of MSA and PD, and demonstrate the potential use of routine MRI in performing their differential diagnosis.
  4882. Brain Structural and Functional Connectivity Alterations in Heart Failure Patients
C. Pan, Y. Pan, W. Tang, Q. Xie, T. Jia, Y. Qiu, L. Lu, J. Chen
Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, Guangdong, China
Impact: This study provides insights into the neurological consequences of heart failure, potentially guiding the development of interventions for associated cognitive decline.
  4883. Correlation of Gray Matter Volume with Transcriptional and Cellular Characteristics in Post COVID-19 Olfactory Dysfunction Patients
J. Luan, G. Ma
China Japan Friendship Hospital, Beijing, China
Impact: This research identifies critical GMV changes in post-COVID olfactory dysfunction patients, linking them to specific genetic and cellular pathways. These findings can inform future therapeutic strategies aimed at restoring olfactory function and understanding post-COVID neurological sequelae.
  4884. Quantification of gray matter abnormalities in systemic lupus erythematosus patients by synthetic MRI
K. Deng, M. Jiang, C. Wu, W. Cui, L. Long
The First Affiliated Hospital of Guangxi Medical University, Nanning, China
Impact: The microstructural abnormalities of the limbic system may be a significant factor contributing to anxiety in patients with systemic lupus erythematosus.
  4885. Microstructural differences in white matter tracts in Alzheimer’s disease, cerebrovascular disease, and Parkinson's disease
D. Broberg, R. Swartz, A. Lang, O. Investigators, A. Roberts, R. Bartha
Western University, London, Canada
Impact: White matter tract microstructure is slightly more preserved in Parkinson’s compared to Alzheimer’s or cerebrovascular disease. These results reinforce the need for higher-quality, advanced diffusion imaging techniques to detect the more subtle white matter degeneration in Parkinson’s disease patients.
  4886. Prediction of Lesion Growth in Multiple Sclerosis: A longitudinal Study with High-resolution Whole-brain MRSI
B. Bo, T. Sheng, W. Tang, Z. Meng, Y. Zhao, Y. Li, W. Jin, Z-P Liang, X. Chen, Y. Li
Shanghai Jiao Tong University, Shanghai, China
Impact: High-resolution whole-brain MRSI provides a promising tool for predicting lesion growth and stratifying patients with higher risk of enlarging lesions during short-term follow-up in MS.
  4887. Precise Quantitative Assessment of Hippocampal Subregional Structural Changes Associated with Cerebral Small Vessel Disease
B. Chen, Y. Fu, L. Guo, C. Liang, C. Sui, Y. Gao, N. Wang, X. Zhang, Y. Wang, Z. Cheng, P. Liang, Y. Chen, X. Huo, F. Zhang
Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, Jinan, China, China
Impact: This study provides data on HP subregion volume changes related to CSVD load, providing new evidence for the mechanism of cognitive-motor function impairment in CSVD, and offering the potential for more precise imaging markers.
  4888. High resolution sub-voxel magnetic susceptibility source separation of pigeon head at 14.1T
H. Yang, L. Wang, Z. Li, J. Li, M. Wang, C. Tian, Q. Ye
High Magnetic Field Laboratory, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, China
Impact: The distribution of paramagnetic and diamagnetic susceptibility disentangled by χ-separation could provide new insights into the understanding of the mechanisms by which pigeons sense and use the Earth’s magnetic field for orientation and navigation.
  4889. Brain age is stable across the menstrual cycle: results from a high-density sampling study
L. Wood, M. Wright, I. Driver, K. Murphy, H. Chandler
Cardiff University Brain Research Imaging Centre (CUBRIC), Cardiff University, Cardiff, United Kingdom
Impact: Menstrual cycle phases may not provide a sufficient representation of endocrine influences on neuroanatomy. Therefore, future research should investigate the potential effect of measured ovarian hormone levels on brain morphology, utilizing an age prediction framework.
  4890. Altered brain iron deposition patterns in iron deficiency anemia
H. Salcudean, C. González-Zacarías, S. Mejia, E. Carpenter, B. Xu, S. Suriany, S. Verma, A. Joshi, P. Chiarelli, R. Leahy, J. Wood
Children's Hospital Los Angeles, Los Angeles, United States
Impact: This is the first study to demonstrate abnormal brain iron deposition in IDA patients, proportional to IDA severity. Brain iron deposition may provide pathophysiological insight into cognitive dysfunction and serve as an imaging biomarker to guide iron replacement strategies. 
  4891. Economical and Diagnostic Quality Aspects Relevant for a Radiology Department Considering Implementation of Deep Learning – Augmented MRI
R. Bammer, J. Warner, J. Richer, C. Blackmore, D. Staeb, J. Jin, R. Blagin, D. Anderson, D. Saddik, A. Stemmer, D. Nickel, K. O'Brien, S. Amukotuwa
Monash University, Clayton, Australia
Impact: We identified the most time-consuming scan protocols by weighting the frequency of utilization by protocol duration. Leveraging 2D+3D DL reconstruction, these protocols were dramatically shortened, freeing up approximately 34% of MRI time, allowing increased throughput while improving diagnostic quality.
  4892. DISTRIBUTION OF PARAMAGNETIC IONS IN EX-VIVO HUMAN BRAIN SAMPLES USING ELECTRON PARAMAGNETIC RESONANCE SPECTROSCOPY
J. Azevedo, F. Otsuka, R. Rodriguez, A. Avanzine, V. Souza, F. Jr, M. Otaduy, C. Salmon
Graduate Program in Neurology, FMRP, University of São Paulo, Ribeirão Preto, Brazil
Impact: This research suggests that copper-iron balance in the brain could serve as an indicator of healthy metal regulation, with implications for neurodegenerative disease research and in vivo brain metal monitoring.
  4893. Ultra-low Field Portable MRI as a Neuroimaging Tool to Identify and Characterize Brain Atrophy in Patients with Neurodegenerative Diseases
A. Pathakamuri, H. Kazimuddin, J. Kwan, L. Turtzo, L. Latour, S. Horovitz
National Institute of Neurological Disorders and Stroke, Bethesda, United States
Impact: Ultra-low field (ULF), portable MRI can identify brain atrophy with a similar sensitivity and specificity as standard 3T MRI. ULF may serve as a more accessible clinical research and diagnostic tool to identify and understand neurodegenerative disease mechanisms. 
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