ISMRM25 - X-Nuclei & Hyperpolarization

ISMRM & ISMRT Annual Meeting & Exhibition • 10-15 May 2025 • Honolulu, Hawai'i

X-Nuclei & Hyperpolarization

Weekend Course

ORGANIZERS: Shaoying Huang, Rolf Schulte, Xiaoliang Zhang

Saturday, 10 May 2025

311

08:00 - 11:50

Moderators: Wei Chen & Joshua Kaggie

Skill Level: Intermediate to Advanced

Session Number: WE-07

No CME/CE Credit

Session Number: WE-07

Overview
X-nuclei journey from basics to advanced techniques and applications, linking the physics principles with the engineering requirements/needs.
This course includes 8 lectures and 2 meet the teachers sessions, organized as follows:
1- Basic physics of x-nuclei and hyperpolarization
2- MR Hardware for x-nuclei: broadband amplifiers, dual-tuned coils
3- Engineering aspects of hyperpolarization: dDNP, PHIP, SEOP
4- Acquisition and reconstruction methods for x-nuclei MR imaging and spectroscopy
5- Meet the teachers
6- 13C metabolic imaging
7- 129Xe lung imaging
8- Sodium MRI
9- Other nuclei: 2H, 7Li, 17O, 31P, 39K, etc.
10- Meet the teachers

Target Audience
Physicists and engineers.

Educational Objectives
As a result of attending this course, participants should be able to:
• Describe spatial encoding and how to navigate through k-space;
• Explain how to accelerate scans; and
• Describe the acquisition chain.

08:00		Basic Physics of X-nuclei & Hyperpolarization Peder Larson
08:25		RF Hardware for X-Nuclei View Presentation Video Tanja Platt Impact: In this talk, X-nuclei RF hardware requirements and developments will be presented including state-of-the-art RF coil developments for various X-nuclei and body regions.
08:50		Engineering Aspects of Hyperpolarization: dDNP, PHIP, SEOP Adam Gaunt
09:15		Acquisition & Reconstruction Methods for X-Nuclei MR Imaging & Spectroscopy View Presentation Video Jeremy Gordon Impact: This presentation will cover the fundamentals of how to acquire and reconstruct x-nuclei MR images and will introduce the audience to some of the challenges associated with x-nuclei MRI.
09:40		Break & Meet the Teachers
10:10		Clinical Hyperpolarised 13C MRI: The Past, The Present & The Future View Presentation Video Ines Horvat-Menih Impact: Clinical hyperpolarised ¹³C-MRI is an emerging metabolic imaging tool, which shows potential to aid management in several clinical fields. This talk will aim to summarise the current research and innovation, and provide future directions to evaluate its potential for clinical translation.
10:35		Hyperpolarized 129Xe MRI: Advancing Diagnosis & Management of Lung Disease View Presentation Video Sean Fain Impact: This presentation will cover the history, methodology and application of hyperpolarized noble gas MRI, focusing principally on advances using 129Xe MRI in chronic lung disease.
11:00		Multi-Nuclei (31P and 23Na) MR in Clinical Research: Applications in Brain & Liver × Video Permission Withheld Fuhua Yan, Naying He, Huimin Lin Impact: Discover the cutting-edge applications of ³¹P and ²³Na MR in brain and liver. This lecture bridges theory with clinical practice, exploring technical advances and emerging applications in neurological and hepatic disorders.
11:25		Sodium MRI View Presentation Video Frank Riemer Impact: Learn about the physics behind 23Na: Background on quadrupole moment, relaxation times and signal contributions from different tissue compartments. Following on some applications of 23Na will be presented highlighting studies in different organs, diseases and general applications.