MR Spectroscopy of Brain: Animal Models

Room 201 C
10:30 – 12:30

Chairs: Dieter Leibfritz and Zaver Bhujwalla

10:30 618. 13C NMR Spectroscopy Investigation of the Relationship between Brain Glucose Metabolism and Glutamatergic Neuronal Activity under Pharmacologically Stimulated Condition, N.R. Sibson, G.F. Mason, D.L. Rothman, K.L. Behar and R.G. Shulman, Yale University School of Medicine, New Haven, CT, USA.
10:42 619. A First Step Towards 13C Isotopomer Analysis In vivo. In Vivo Detection of Homonuclear 13C Spin Couplings During [1, 2-13C2] Glucose Metabolism in Rat Brain, G. Karelson, J. Seelig and B. Künnecke, Biocenter of the University, Basel, Switzerland.
10:54 620. Focal Ischemia and Remote Neuronal Damage in Apolipoprotein E-Deficient Mice, S.T. Pendlebury, C. Liess, P. Cassidy, P. Styles and P.M. Matthews, John Radcliffe Hospital, Oxford, UK.
11:06 621. Assessment of Cerebral Protection during Unilateral Antegrade Cerebral Perfusion for Aortic Surgery: A Localized MR Spectroscopic Imaging Study in a Pig Model, J. Ye, G.P. Dai, P. Kozlowski, L.N. Ryner, J. Sun, L. Yang, R. Summers, T.A. Salerno, R.L. Somorjai and R. Deslauriers, National Research Council of Canada, Winnipeg, Manitoba, Canada and State University of New York at Buffalo, New York, USA.
11:18 622. Towards an In Vivo Neurochemical Profile: Quantification of 18 Metabolites in 1H NMR Spectra of Rat Brain at TE=2ms, J. Pfeuffer, I. Tkac, S.W. Provencher and R. Gruetter, University of Minnesota Medical School, Minneapolis, MN, USA and MPI for Biophysical Chemistry, Göttingen, Germany.
11:30 623. Exponential Decrease Over Time in N-acetyl Aspartate Levels in the Absence of Neuronal Loss and Increases in Glutamine and Glucose in Transgenic Huntington's Disease Mice, B.G. Jenkins, P. Klivenyi, E. Kustermann, O.A. Andreassen, R.J. Ferrante, B.R. Rosen and M.F. Beal, Massachusetts General Hospital, Charlestown, MA, USA.
11:42 624. Serial 1H-MRS Study of Metabolic Impairment in a Chronic Primate Model of Huntington's Disease, C. Dautry, F. Condé, E. Brouillet, V. Mittoux, M. Flint Beal, G. Bloch and P. Hantraye, URA CEA CNRS and SHFJ, DRM, DSV, CEA, Orsay, France and Cornell University Medical College, New York, NY, USA.
11:54 625. HRMAS 1HMRS Reveals Early Reversible Neurological Injury in SIV Infected Macaques, L.L. Cheng, S.V. Westmoreland, A.A. Lackner and R.G. Gonzalez, Harvard Medical School, Boston, MA, USA.
12:06 626. Single-Scan Diffusion Trace 1H MRS and MRI in Experimental Hydrocephalus; Compartmentation of Metabolites, K.P.J. Braun, R.A. de Graaf, F. ter Veld, L.L.F.M. Ciotti, W.P. Vandertop and K. Nicolay, Utrecht University, Utrecht, The Netherlands.
12:18 627. Changes in Apparent Diffusion Coefficients of Metabolites in Rat Brain After Occlusion of the Right MCA Measured by 1H NMR Spectroscopy with Effective Homonuclear Decoupling, W. Dreher, E. Busch, C. Meier, D. Mayer, A. Ebel and D. Leibfritz, Universität Bremen, Bremen, Germany and Universität Essen, Essen, Germany.

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