Tumor Spectroscopy and Imaging: Models

Room 204 C
10:30 – 12:30

Chairs: Jason A. Koutcher and Sabrina M. Ronen

10:30 488. Detection of Metabolic Changes Associated with Fas- and Chemotherapy-Induced Apoptosis Using MRS, N.M. Al-Saffar, P.A. Clarke, F. DiStefano, M.O. Leach and S.M. Ronen, Royal Marsden Hospital, Sutton, Surrey, UK.
10:42 489. 1H MRS of Rat Glioma in vivo: Role of Polyunsaturated Fatty Acids in Apoptotic Cell Death as Induced by Gene Therapy, J.M. Hakumäki, H. Poptani, A.M. Puumalainen, S. Ylä-Herttuala and R.A. Kauppinen, University of Kuopio, Kuopio, Finland.
10:54 490. The Anti-Inflammatory Agent Indomethacin Reduces the Malignant Phospholipid Phenotype of Metastatic Human Breast Cancer Cells, Z.M. Bhujwalla, K. Natarajan, E.O. Aboagye, N. Mori, D. Artemov, U. Pilatus and V.P. Chacko, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
11:06 491. Quantiation of Cytosine Deaminase Transgene Expression in Tumors Using 19F-MRS, L.D. Stegman, B. Beattie, E. Kievit, T.S. Lawrence, A. Rehemtulla, J.G. Tjuvajev, R.G. Blasberg and B.D. Ross, University of Michigan, Ann Arbor, MI, USA and Memorial Sloan Kettering Cancer Center, New York, NY, USA.
11:18 492. Measurement of Nitric Oxide in Mice using EPR and Spin Trapping with Fe-(DETC)2 After Irradiation, J.A. O'Hara, O.Y. Grinberg and H.M. Swartz, Dartmouth Medical School, Hanover, NH, USA.
11:30 493. Intracellular Acidification Increases Thermal Sensitivity for the RIF-1 Tumor In Vivo, W.M. Spees, J.L. Evelhoch and J.J.H. Ackerman, Washington University, St. Louis, MO, USA and Wayne State University, Detroit, MI, USA.
11:42 494. Effect of Hyperglycemia and Inhibition of Mitochondrial Respiration on Intra- and Extracellular pH in a Human Melanoma Xenograft, R. Zhou, N. Bansal, J.D. Glickson and D.B. Leeper, University of Pennsylvania and Thomas Jefferson University, Philadelphia, PA, USA.
11:54 495. Comparison of Changes in Gradient-Echo 1H MR Image Intensity and pO2 in Rodent Tumours in Response to Carbogen Breathing, R.J. Maxwell, S.P. Robinson, D.J.O. McIntyre, J.R. Griffiths and B. Vojnovic, Gray Laboratory Cancer Research Trust, Northwood, Middlesex, UK and St. George's Hospital Medical School, London, UK.
12:06 496. MR Correctly Predicts the Relative Effect of Two Tumor Oxygenating Agents on Hypoxic Fraction in Rodent BA1112 Tumors, H.A. Al-Hallaq, M. Zamora, J.N. River and G.S. Karczmar, University of Chicago, Chicago, IL, USA.
12:18 497. Delineation of Tumor and Normal Tissue Using Responses to Vasoactive Challenge, Y. Cao, S.L. Brown, J.R. Ewing, R.A. Knight, Q. Jiang, P. Jiang and A. Kolozsvary, Henry Ford Health System, Detroit, MI, USA.

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