ISMRM Workshops: Learn, Share Research & Network

ISMRM Workshop on

Diffusion MRI:

From Research to Clinic

10-14 October 2022

Postillion Hotel & Convention Centre Amsterdam, Amsterdam, The Netherlands

Registration is SOLD OUT

On-site and late registrations will not be offered!

Organizers

Chair:
Ivana Drobnjak, Ph.D.

Sustainability

ISMRM's Sustainability Initiatives

Supporters & Declarations

Faculty declarations will be available approx. 2 weeks before workshop start.

Overview & Program

Workshop Overview

This workshop aims to elaborate a common vision for the future of the field and what is needed for its translation to everyday clinical practice. Key topics include the latest methodological developments in hardware and acquisitions, microstructure modelling, and the use of AI. A special attention is also given to novel developments of diffusion MRI outside the brain (prostate, fetal, placental, muscle, and breast, amongst others). The workshop will then focus on bridging the gap between research and clinic and establishing the translational path of the different themes, focusing on better links between experiments and modelling, consolidation of current approaches, and current and potential future integration into the clinical studies and practice.

The workshop will start with an optional educational "bootcamp" day designed for students and researchers new to the field of diffusion MRI. Here the lectures will be targeted and balanced for an audience with both basic science or technical backgrounds, as well as more applied or clinical backgrounds. Attendees will learn the basics of diffusion MRI, sequence design and contrast mechanisms, preprocessing, microstructure measurements and their validation, interpretation, and their clinical and research applications. Introductory lectures on anatomy and basic physiology will also be offered to better present the different areas of application of diffusion MRI. Sessions are divided into themes and each is followed by an expert led discussion spanning both Ph.D. and M.D. leaders in the field to provide both the scientific and clinical insights into the topics. The bootcamp will have an informal, intimate format to enable attendees to interact closely with lecturers, gain practical insights into working in the field of diffusion MRI, and prepare them for the formal workshop program following.

The formal workshop program will feature invited scientific presentations, proffered papers, poster sessions, and panel discussions. It has been carefully structured to be interdisciplinary and to bring together diffusion MRI researchers and clinicians, and it offers CME credits. The workshop is designed to be highly interactive, with regular scheduled breaks between sessions for informal discussions and poster presentations. There will be a balance of focused sessions led by leaders in the field and proffered scientific abstracts. Structured meals, receptions, and our highly popular "poster bars" for discussion and networking are integrated into the structure of the program.

Target Audience:

This workshop is designed for researchers (including Ph.D. students and postdocs); clinicians (e.g., neurologists, radiologists, neurosurgeons); MR technologists; government regulatory experts; nonprofit and academic groups interested in early diagnosis and public health; and members of the ISMRM Diffusion MRI and White Matter Study Groups.

The topics we propose are highly relevant for our attendees interested in continuing medical education. They will provide knowledge of new technical and methodological approaches in using diffusion MRI to diagnose and monitor a range of medical conditions, e.g. tissue injury, stroke, neurological conditions, prostate cancer, and cancer in general, etc. Furthermore, they will provide methods for utilizing this knowledge and resources needed for it.

Educational Objectives:

Upon completion of this activity, participants should be able to:

  • Review the fundamentals of diffusion acquisition, modelling, analysis and applications;
  • Prepare an overview of key recent developments in diffusion MRI: acquisition and processing, tractography and connectivity, microstructure, and hardware advances;
  • Describe the development and application of diffusion MRI outside the brain;
  • Review the current uses of AI in diffusion MRI;
  • Recognize the current limitations in diffusion MRI, both from the standpoint of physical limits and obstacles to clinical translation;
  • Develop their own view on the common vision for the future of the diffusion MRI and its translation to everyday clinical practice;
  • Explain the translational pathway from research to the clinic including: modelling, experiments, validation, application, and the corresponding links;
  • Examine both the established and the more recent developments in diffusion MRI for use in the clinical applications; and
  • Discuss setting guidelines on DTI, diffusion MRI processing, small-animal and ex vivo imaging, clinical tractography, IVIM and diffusion outside the brain, and clinical dMRI.

Preliminary Program

Badge Pickup & Setup - Sunday, 09 October 2022 (No CME Available)

16:00

Badge Pickup & Speaker Upload Available (until 18:00)

Day 1 - Monday, 10 October 2022 - Optional Boot Camp (8.00 CME Available)

07:00

Badge Pickup & Speaker Upload Available

08:10

Welcome to the Bootcamp

Boot Camp Session 1: Foundations 1

Moderators: Jennifer Campbell, Ph.D. & Valerij G. Kiselev, Ph.D.

08:15

An Intro to MRI & Diffusion

T.B.A.

08:45

Neuroanatomy in Practice: Learning from a Neurosurgical Perspective

Joseph (Yuan-Mou) Yang, M.D., Ph.D.
Royal Children's Hospital
Parkville, VIC, Australia

09:15

Expert-Initiated Discussion: Current Challenges, What We Do/Don't Measure, Common Mistakes, What We Are Still Pursuing

Jennifer Campbell, Ph.D. &
Valerij G. Kiselev, Ph.D.

10:00

Break & Speaker Upload Available

Boot Camp Session 2: Foundations 2

Moderators: Carlo Pierpaoli, M.D., Ph.D. & T.B.A.

10:30

Sequence Design & Contrast Mechansims

Filip A. Szczepankiewicz, Ph.D.
Lund University
Lund, Sweden

11:00

Acquistion Approaches: From Basic to Advanced

Ben Jeurissen, Ph.D.
University of Antwerp
Antwerp, Belgium

11:30

Expert-Initiated Discussion: Current Challenges & Controversies

Claudia A. Gandini Wheeler-Kingshott, Ph.D. & Carlo Pierpaoli, M.D., Ph.D.

12:15

Lunch & Speaker Upload Available

Boot Camp Session 3: Analysis & Applications 1

Moderators: Maxime Descoteaux, Ph.D. & Dara M. Cannon, Ph.D.

14:00

Pre-Processing: Pipelines & Pitfalls

Martijn Froeling, Ph.D.
Utrecht University
Utrecht, The Netherlands

14:30

Qualitative Applications of DWI Data

Thijs Dhollander, Ph.D.
Murdoch Children's Research Institute
Royal Children's Hospital
Parkville, VIC, Australia

15:00

Expert-Initiated Discussion: Current Challenges & Controversies in Clinical & Neuroscientific Applications (Stroke, Tractography, etc.)

Maxime Descoteaux, Ph.D. &
Dara M. Cannon, Ph.D.

15:45

Break & Speaker Upload Available

Boot Camp Session 4: Analysis & Applications 2

Moderators: Tim B. Dyrby, Ph.D. & Els Fieremans, Ph.D.

16:30

Why We Need Quantitative Measures of Microstructure

Kouhei Kamiya, M.D., Ph.D.
Toho University
Tokyo, Japan

17:00

Overview of Quantitative Approaches & Applications

Robert E. Smith, Ph.D.
Florey Institute of Neuroscience & Mental Health
Heidelberg, VIC, Australia

17:30

Expert-Initiated Discussion: Current Challenges & Controversies in Microstructure & Connectivity Measures

Tim B. Dyrby, Ph.D.
Els Fieremans, Ph.D.

18:15

Adjournment

Day 2 - Tuesday, 11 October 2022 (5.75 CME Available)

07:30

Badge Pickup & Speaker Upload Available

Session 1: Introduction

Moderator: Ivana Drobnjak, Ph.D.

08:30

Welcome

Ivana Drobnjak, Ph.D. & Workshop Organizers

08:45

Keynote: DWI From Research to Clinic

Pratik Mukherjee, M.D., Ph.D.
San Francisco Veterans Affairs Medical Center
San Francisco, CA, USA

Session 2: Acquisition & Processing

Moderators: Sune N. Jespersen, Ph.D. & Rita G. Nunes, D.Phil.

09:30

Beyond Single Diffusion Encoding: Applications in the Medical Sciences

Markus Nilsson, Ph.D.
Lund University
Lund, Sweden

10:00

Imaging Moving Structures: Fetal & Placental Imaging

Jana Hutter, Ph.D.
King's College London
London, England, UK

10:30

Break & Speaker Upload Available

11:00

A Data Driven Variabiilty Assessment of Brain Diffusion MRI Preprocessing Pipelines

Jelle Veraart, Ph.D.
New York University Langone Medical Center
New York, NY, USA

Proffered Papers - Oral Session

11:30

mrHARDIflow: A Reproducible Pipeline for Robust Preprocessing & Analysis of Non-Human Primates Diffusion MRI

Alex Valcourt Caron, M.Sc.
Université de Sherbrooke
Sherbrooke, QC, Canada

11:40

Elimination of Distortion & Slice Aliasing in 3D Diffusion MRI by Integrating Multiple Sampling Strategies Into Reconstruction

Ziyu Li, B.Sc.
University of Oxford
Oxford, England, UK

11:50

Segmented Spiral Diffusion Acquisitions Using Motion-Compensated Diffusion Encoding & High-Performance Gradients

Eric Michael, M.Sc.
ETH
Zurich, Switzerland

12:00

Expert-Led Panel Discussion

Sune N. Jespersen, Ph.D. &
Rita G. Nunes, D.Phil.

13:00

Lunch & Speaker Upload Available

Session 3: Tractography & Connectivity

Moderators: Jacques-Donald Tournier, Ph.D. & T.B.A. & Ragini Verma, Ph.D.

13:45

Challenges & Hidden Pitfalls of Tractography Today

Francois Rheault, Ph.D.
Université de Sherbrooke
Sherbrooke, QC, Canada

14:15

Connectional Anatomy Across Scales: Linking Diffusion MRI to Microscopy

Anastasia Yendiki, Ph.D.
A.A. Martinos Center for Biomedical Imaging
Charlestown, MA, USA

14:45

Multimodal Integration for Global Tractography

Simona Schiavi, Ph.D.
University of Genoa
Genova, Italy

Proffered Papers - Oral Session

15:15

Hierarchical Modelling of Crossing Fibres in the White Matter

Hossein Rafipoor, Ph.D. Student
University of Oxford
Oxford, England, UK

15:25

Walking in the Dark: Spherical Deconvolution Methods in Cortical Gray Matter

Andrey Zhylka , M.Sc.
Eindhoven University of Technology
Eindhoven, The Netherlands

15:35

Reducing Redundancy in Tractography Using Blurred Streamlines

Ilaria Gabusi, M.Sc.
University of Verona
Verona, Italy

15:45

Expert-Led Panel Discussion

Jacques-Donald Tournier, Ph.D. & T.B.A.
Ragini Verma, Ph.D.

16:30

Break & Speaker Upload Available

Session 4: Power Pitches, Poster & Consensus Sessions (No CME Available)

Moderator: Flavio Dell'Acqua, Ph.D. & T.B.A.

17:00

Supporter Presentation (No CME Available)

 

Power Pitch Session (No CME Available)
17:10

18:10

Poster Viewing Session (No CME Available)
Drinks & Snacks

19:00

Networking Dinner

20:30

Optional Round-Table Discussion on Consensus Paper (No CME Available)
DW Image Processing

Facilitator: Jelle Veraart, Ph.D.

21:30

Adjournment

Day 3 - Wednesday, 12 October 2022 (5.50 CME Available)

08:00

Badge Pickup & Speaker Upload Available

Session 5: Microstructure of the Brain & Validation

Moderators: Dmitry S. Novikov, Ph.D. & Carl-Fredrik Westin, Ph.D.

09:00

Compartmental Modeling in Brain White Matter: Standard Model

Amy Howard, Ph.D.
University of Oxford FMRIB Centre
Oxford, England, UK

09:30

Beyond Standard Model/Time-Dependent Diffusion in Brain

Hong-Hsi Lee, M.D., Ph.D.
Massachusetts General Hospital
Charlestown, MA, USA

10:00

Gray Matter: Modeling & Validation

Marco Palombo, Ph.D.
Cardiff University
Cardiff, Wales, UK

10:30

Break & Speaker Upload Available

11:00

Brain Microstructure Imaging: Applications & Validation

Manisha Aggarwal, Ph.D.
John Hopkins School of Medicine
Baltimore, USA

Proffered Papers - Oral Session

11:30

Comparison of Diffusion MRI White Matter Models With Microstructure Metrics Derived From 3D Electron Microscopy

Ricardo Coronado Leija, Ph.D.
NYU Grossman School of Medicine
New York, NY, USA

11:40

Optimizing the NEXI Acquisition Protocol for Human Gray Matter Microstructure Mapping on a Clinical MRI Scanner Using Explainable AI

Quentin Uhl, M.Sc.
Lausanne University Hospital (CHUV)
Cugy, Switzerland

11:50

Correlation Tensor MRI Unravels Dynamic Alterations in Underlying Kurtosis Sources Along Stroke Progression

Rita Alves, M.Sc.
Champalimaud Foundation
Lisbon, Portugal

12:00

Expert-Led Panel Discussion

Dmitry S. Novikov, Ph.D.
Carl-Fredrik Westin, Ph.D.

12:45

Lunch & Speaker Upload Available

Session 6: Microstructure Body & Cancer

Moderators: Christian Beaulieu, Ph.D. & Denis Le Bihan, M.D., Ph.D.

13:45

Applications for Prostate Cancer Imaging

Eleftheria Panagiotaki, Ph.D.
University College London
London, England, UK

14:15

Muscle Microstructure

David Berry, Ph.D.
University of California, San Diego
San Diego, Ca, USA

14:45

IVIM & Non-Gaussian Diffusion: Applications to Breast Tissue & Cancer

Mami Iima, M.D., Ph.D.
Kyoto University Graduate School of Medicine
Kyoto, Japan

Proffered Papers - Oral Session

15:15

Disentangling Intracellular & Extracellular Contributions to Apparent Diffusion Coefficients in Bone Metastases Using Histology

Alonso Garcia-Ruiz, M.Sc.
Vall d'Hebron Institute of Oncology
Barcelona, Spain

15:25

300 mT/M Diffusion MRI Beyond the Brain: Probing Restricted Diffusion in Prostate Cancer

Malwina Molendowska, M.Sc.
Cardiff University Brain Research Imaging Centre (CUBRIC)
Cardiff, Wales, UK

15:35

Decoding Liver Intra-Tumour Heterogeneity With Co-localized CT & Multi-parametric MRI

Olivia Prior Palmonares, M.Sc.
Vall d'Hebron Institute of Oncology
Barcelona, Spain

15:45

Expert-Led Panel Discussion

Christian Beaulieu, Ph.D.
Denis Le Bihan, M.D., Ph.D.

16:30

Break & Speaker Upload Available

Session 7: Power Pitches, Poster & Consensus Sessions (No CME Available)

Moderators: Ileana O. Jelescu, Ph.D. & T.B.A.

Power Pitch Session (No CME Available)
17:00

18:00

Poster Viewing Session (No CME Available)
Drinks

20:30

Optional Parallel Round-Table Discussions on Consensus Papers (No CME Available)

• Recommendations & Guidelines for Small Animal & Ex Vivo Diffusion Imaging

Facilitators: Ileana O. Jelescu, Ph.D. & Kurt Schilling, Ph.D.

• Clinical Diffusion Tractography

Facilitator: Flavio Dell'Acqua, Ph.D.

21:30

Adjournment & Dinner on own

Day 4 - Thursday, 13 October 2022 (5.50 CME Available)

08:00

Badge Pickup & Speaker Upload Available

Session 8: From Research to the Clinic

Moderators: Shawna Farquharson, Ph.D. & Susie Yi Huang, M.D., Ph.D.

09:00

Imaging Cancer in the Body: What I Have & What I Want

Eddie W. Lau, M.B.B.S.,FRANZCR
Austin Hospital
Heidelberg, VIC, Australia

09:30

Understanding Disease Progression in MS: What I Have & What I Want

Francesca Bagnato, M.D., Ph.D.
Vanderbilt University Medical Center
Nashville, TN, USA

10:00

Presurgical Planning & Intraoperative Neuronavigation in Neurosurgery: What I Have & What I Want

Joseph (Yuan-Mou) Yang, M.D., Ph.D.
Royal Children's Hospital
Parkville, VIC, Australia

10:30

QDWI - The Neuroradiologist's Perspective: Survey Results

Carlo Pierpaoli., M.D., Ph.D.
NIBIB / NIH
Bethesda, MD, USA

10:45

Break & Speaker Upload Available

Proffered Papers - Oral Session

11:15

Linking Disability & White Matter Microstructure in Multiple Sclerosis

Valentin Stepanov, M.D.
NYU Grossman School of Medicine
New York, NY, USA

11:25

Structural Connectivity of Visual Pathways in Children With Perinatal Stroke

Meghan Maiani, MSc/PhD student
University of Calgary
Calgary, AB, Canada

11:35

Multi-Site Normative Modeling of Diffusion MRI Metrics in Carriers of 16p11.2 Copy Number Variants

Julio Villalon-Reina, M.D, Ph.D.
University of Southern California
Los Angeles, NY, USA

11:45

Expert-Led Panel Discussion

Shawna Farquharson, Ph.D. & Susie Yi Huang, M.D., Ph.D.

12:30

Lunch & Speaker Upload Available

Session 9: Hardware Advances

Moderators: Gigi Galiana, Ph.D. & Jennifer McNab, Ph.D.

13:30

Research Applications Using High Performance Gradients for Whole Body Scanners

Peter Van Zijl, Ph.D.
John Hopkins University School of Medicine
Baltimore, MD, USA

14:00

Clinical Applications on the Connectome

Susie Yi Huang, M.D., Ph.D.
Massachusetts General Hospital
Boston, MA, USA

14:30

Magnus High Performance Gradients & Head Only Scanners

Thomas K.F. Foo, Ph.D.
GE Global Research
Niskayuna, NY, USA

15:00

Dynamic Field Monitoring & Applications to Diffusion Imaging

Bertram J. Wilm, Ph.D.
Skope Magnetic Resonance Technologies
Zürich, Switzerland

15:30

Break & Speaker Upload Available

Proffered Papers - Oral Session

15:50

Prostate Nonlinear Gradient Coil Field & Eddy Current Characterization

Nahla Elsaid, Ph.D.
Yale University
New Haven, CT, USA

16:00

Measuring Time Dependent Diffusion Kurtosis in Human Gray Matter Using a High-Performance Head-Only Gradient System at 3T

Erpeng Dai, Ph.D.
Stanford University
Stanford, CA, USA

16:10

T.B.A.

T.B.A.

16:20

Expert-Led Panel Discussion

Gigi Galiana, Ph.D. &
Jennifer McNab, Ph.D.

17:05

Break & Speaker Upload Available

Session 10: Power Pitches, Poster & Consensus Sessions (No CME Available)

Moderators: Kurt Schilling, Ph.D. & T.B.A.

Power Pitch Session (No CME Available)
17:15

18:15

Poster Viewing Session (No CME Available)
Drinks & Snacks

20:30

Optional Parallel Round Table Discussions on Consensus Papers (No CME Available)
Best Practices for Quantitative Diffusion MRI in Clinical & Neuroscience Research

Facilitators: Shawna Farquharson, Ph.D. &
Carlo Pierpaoli, M.D., Ph.D.

21:30

Adjournment & Dinner on own

Day 5 - Friday, 14 October 2022 (2.00 CME Available)

08:00

Badge Pickup & Speaker Upload Available

Session 11: AI & Big Data

Moderators: Daniel C. Alexander, Ph.D. & Kurt Schilling, Ph.D.

09:00

Machine Learning for Diffusion MRI Data Analysis

Oliver J. Gurney-Champion, Ph.D.
Amsterdam University Medical Center
Amsterdam, The Netherlands

09:30

Deep Learning for Tractography & Connectivity Mapping

Peter Neher, Ph.D.
German Cancer Research Center
Heidelberg, Germany

Proffered Papers - Oral Session

10:00

You Only Autoencode Once

Jon Haitz Legarreta, M.Sc.
Université de Sherbrooke
Sherbrooke, QC, Canada

10:10

Differentiation of White Matter Histopathology Using B-Tensor Encoding & Machine Learning

Ricardo Rios-Carrillo, M.Sc.
UNAM
Guanajuato, Mexico

10:20

Diffusion MRI tractometry findings in Dystonia: a UK Biobank Study

Claire Maclver, M.Sc., MBBCh
Cardiff University
Cardiff, Wales, UK

10:30

Expert-Led Panel Discussion

Daniel C. Alexander, Ph.D. &
Kurt Schilling, Ph.D.

11:15

Break

Session 12: Future Directions

Moderator: Ivana Drobnjak, Ph.D.

11:45

Panel Discussion: Strategic Directions

T.B.A.

12:45

Workshop Recap, Reflections & Awards

T.B.A.

13:30

Farewells

🡄 Return to Future Workshops Page   |   Questions? Contact us at info@ismrm.org.

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