ISMRM Workshops: Learn, Share Research & Network

ISMRM Workshop on

MR Spectroscopy:

Frontiers in Molecular & Metabolic Imaging

15-18 October 2024

Boston, MA, USA

Abstract submission deadline:

Call for Abstracts & Stipend Applications

Organizers

Co-Chair:
Ovidiu C. Andronesi, M.D., Ph.D.
Chao Ma, Ph.D.

Registration & Travel

Travel & Nearby Housing Info

Registration Coming Soon

Sustainability

ISMRM Sustainability Initiatives

Supporters & Declarations

Faculty declarations will be available approximately two weeks before the workshop begins.

Overview & Program

Workshop Overview

Magnetic resonance spectroscopy (MRS) can simultaneously image up to 20 metabolites in the brain and assess their concentration and the dynamic change of their concentrations under functional tasks. MRS is capable of measuring intrinsic metabolism non-invasively without the need of contrast agents and can probe metabolic enzymatic rates that are not accessible by other imaging techniques. Numerous studies have demonstrated the considerable value of MRS for clinical applications. Great progress has been realized over the last few years in the performance of MRS resulting in fast and high-resolution imaging methods with robust performance in clinical and research investigations.

The ability to probe metabolic alterations is important to understand disease mechanisms and for patient management, including diagnosis, treatment planning, and treatment response assessment. In addition, MRS allows to probe metabolism in healthy individuals and in healthy tissues of patients providing important information about normal function.

Target Audience

Scientists and clinicians interested in learning the state of the art of in-vivo MRS to image metabolism under healthy and disease conditions. The program will combine lecture sessions provided by experts in the field and abstract sessions to present the work of attendees. This meeting will provide a forum to share best practices, disseminate knowledge and methodology, and create consensus and standardization through panel discussions and practical demonstrations.

Educational Objectives

This workshop will present the state of the art in technical performance and clinical applications of MRS, which will be relevant to a broad audience of scientists and clinicians. In particular, the topics of interest include: the fundamentals of MRS methodology; biological and clinical relevance of metabolism; advanced MRS methodology; and clinical and pre-clinical applications in healthy conditions and diseases such as cancer, neuropsychiatric disorders, and inborn errors of metabolism. Practical sessions of MRS imaging protocols and data analysis will be demonstrated during this workshop as well.

Upon completion of this activity, participants should be able to:

  • Describe metabolism in healthy state and metabolic alterations in disease pathology;
  • Describe acquisition and processing steps of MRS, including pulse sequences and processing software;
  • Summarize state-of-the-art advanced 1H-MRSI methodology;
  • Describe X-nuclei MRS imaging;
  • Describe Hyperpolarization techniques; and
  • Explain complementary modalities of metabolic and molecular imaging

Preliminary Program

Day 1 - Tuesday, 15 October 2024

07:30

Registration & Speaker Upload Available

Session 1: Basics of MRS(I) Part I: Acquisition & Reconstruction

Moderators: T.B.A.

08:00

Opening Statements

T.B.A.

08:30

Metabolism & MRS

T.B.A.

08:50

MRS Data Acquisition

T.B.A.

09:10

MRS Data Processing

T.B.A.

09:30

Spectral Fitting & Quantification

T.B.A.

09:50

Standardization

T.B.A.

10:10

Break & Speaker Upload Available

10:40

Proffered Papers - Oral Session

11:40

Keynote Address: MRS Historical Perspective

T.B.A.

12:20

Lunch & Speaker Upload Available
Poster Viewing

13:30

Poster Session

Session 2: Basics of MRS(I) Part II: Auxiliary Techniques

Moderators: T.B.A.

14:00

B0 Shimming

T.B.A.

14:20

Motion Correction

T.B.A.

14:40

Water & Lipid Suppression

T.B.A.

15:00

Spectral Editing & 2D MRS

T.B.A.

15:20

Functional & Diffusion-Weighted MRS

T.B.A.

15:40

Break & Speaker Upload Available

Session 3: Preclinical MRS

Moderators: T.B.A.

16:10

Experimental Techniques for Preclinical MRS

T.B.A.

16:30

Targeted Metabolomics

T.B.A.

16:50

Metabolic Flux by MRS

T.B.A.

17:10

Pharmacological MRS

T.B.A.

17:30

Consensus on Preclinical MRS

T.B.A.

18:00

Proffered Papers - Oral Session

18:50

Adjourn

Day 2 - Wednesday 16 October 2024

07:30

Registration & Speaker Upload Available

Session 4: Advanced MRSI

Moderators: T.B.A.

08:30

Spectral-Spatial Encoding

T.B.A.

08:50

Undersampling Techniques

T.B.A.

09:10

Ultra-High Field MRSI

T.B.A.

09:30

Special Hardware for MRSI

T.B.A.

09:50

Deep Learning in MRSI

T.B.A.

10:10

Proffered Papers - Oral Session

10:40

Break & Speaker Upload Available

11:40

Keynote Address: MRS(i) State-of-the-Art/New Horizons

T.B.A.

12:20

Lunch & Speaker Upload Available
Poster Viewing

13:30

Poster Session

Session 5: X-Nuclei & Hyperpolarized MRS/MRSI

Moderators: T.B.A.

14:00

31P MRS/MRSI

T.B.A.

14:20

Deuterium Imaging

T.B.A.

14:40

13C MRS/MRSI

T.B.A.

15:00

Hyperpolarized 13C Imaging

T.B.A.

15:20

Spectroscopy in the Millitesla Regime & Non-DNP Hyperpolarization

T.B.A.

15:40

Proffered Papers - Oral Session

16:10

Break & Speaker Upload Available

17:00

Industry/Sponsor Presentations (No CME Available)

18:00

Adjourn

Day 3 - Thursday, 17 October 2024

07:30

Registration & Speaker Upload Available

Session 6: Clinical Applications of MRS

Moderators: T.B.A.

08:30

MRS of Cancer

T.B.A.

08:50

MRS in Neuropsychiatric Diseases

T.B.A.

09:10

MRS in Metabolic & Neurodegenerative Diseases

T.B.A.

09:30

MRS of the Body: Liver, Cardiac, Muscle, etc.

T.B.A.

09:50

Clinical Integration of MRS in Radiological Workflow

T.B.A.

10:10

Proffered Papers - Oral Session

10:40

Break & Speaker Upload Available

11:20

Keynote Address: Molecular Imaging: Breaking Barriers

T.B.A.

12:00

Lunch & Speaker Upload Available
Poster Viewing

13:30

Poster Session

Session 7: Molecular Imaging

Moderator: T.B.A.

14:00

Chemical Exchange Saturation Transfer

T.B.A.

14:20

Positron Emission Tomography

T.B.A.

14:40

Single Photon Emission Computed Tomography

T.B.A.

15:00

Near Infrared Spectroscopy

T.B.A.

15:20

Fluorescence Lifetime Imaging

T.B.A.

15:40

Break & Speaker Upload Available

16:10

Special Guest: Next Generation MRI & Unmet Clinical Needs

T.B.A.

16:40

Shark-Tank Session

18:00

Tour of the Martinos Center (No CME Available)

18:30

Adjourn

Day 4 - Friday, 18 October 2024

07:30

Registration & Speaker Upload Available

Session 8: Metabolomics

Moderators: T.B.A.

08:30

NMR Spectroscopy of Tissue Extracts

T.B.A.

08:50

High-Resolution Magic Angle Spinning (HRMAS)

T.B.A.

09:10

Cellular Metabolomics by NMR & Machine-Learning

T.B.A.

09:30

Mass Spectrometry & In Vivo Microdialysis

T.B.A.

09:50

Multimodal Imaging Platform for Drug Development

T.B.A.

10:10

Infrared & Raman Spectroscopy

T.B.A.

10:30

Break & Speaker Upload Available

11:00

Code & Data Sharing Committee (No CME Available)

T.B.A.

11:30

MRS Challenge

12:00

Conclusions

12:30

Boxed Lunch & Adjourn

🡄 Return to Future Workshops Page   |   Questions? Contact us at info@ismrm.org.

The International Society for Magnetic Resonance in Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.