Molecular & Cellular Imaging Workshop


	ISMRM Central Office 2030 Addison Street Suite 700 Berkeley, CA 94704 Tel: +1 510-841-1899 Fax: +1 510-841-2340 info@ismrm.org We welcome your comments & suggestions for our Web site.

Last updated 09 September 2010

Sunday, 4 February
14:00 – 17:00	Boarding, Registration, Poster Setup

18:00 – 20.30	Dinner

20:30	Opening Remarks	Jeff W.M. Bulte, Ph.D., Johns Hopkins University, Baltimore, Maryland, USA Annemie van der Linden, D.Sc., University of Antwerp, Antwerp, Belgium

20:45	Keynote Speaker	Angelique Louie, Ph.D., University of California, Davis, CA, USA
		Molecular/Cellular MRI: The Past, the Present and the Future

Monday, 5 February
08:00 – 09:00	Breakfast/Registration

9:00	Plenary Speaker 1	Clemens Lowik, Ph.D., University Hospital Leiden, Leiden, The Netherlands
		Optical imaging: What can it do that MRI can’t?

	Oral Session 1: MRI Reporter Genes, Dmitri Artemov, Ph.D., and Eric Ahrens, Ph.D., Moderators
09:45		Michal Neeman Ph.D., Weizmann Institute of Science, Rehovot, Israel *Molecular imaging of gene expression in vascular development*
10:05		Ralph P. Mason Ph.D., UT Southwestern Medical Center, Dallas, TX, USA *A MAGIC approach to gene expression (Magnetic Resonance Assay of Gene Imaging Constructs)*
10:25		Jimmy D. Bell Ph.D., Hammersmith Hospital, London, England, UK *Assessing gene expression by MRI: a reality or just wishful thinking*

10:45	Break

11:05	General Assembly: Closing Discussion on Reporter Genes

11:25	MI but not MRI	Mark Borden, Ph.D., University of California, Davis, CA, USA Strategies in Ultrasonic Molecular Imaging

	Proffered Paper
11:45		E. James Delikatny, Ph.D., University of Pennsylvania, Philadelphia, PA, USA *Design and Characterization of an Enzyme-Activated Probe Highly Specific to Phosphatidylcholine-specific Phospholipase C*

12:05	Lunch

	Oral Session 2: The Bright Future of Manganese, Eric Shapiro, Ph.D., and Louise van der Weerd, Ph.D., Moderators
14:00		Anne-Marie van der Linden, D. Sc., University of Antwerp, Antwerp, Belgium MEMRI: an in Vivo Tool to Study Neuroplasticity
14:20		Tom Chih-Chuang Hu, Ph.D., M.B.A., Medical College of Georgia, Augusta, GA, USA MEMRI: Application to Small Animal Heart Model
14:40		Ichio Aoki, Ph.D., National Institute of Radiological Sciences, Chiba, Japan *Expanding Applications for Manganese-enhanced MRI*

	Proffered Paper
15:00		Youssef Z. Wadghiri, Ph.D., New York University, New York, NY, USA In Vivo µMEMRI Reveals Age-Dependent Hippocampal Dysfunction in a Tangle Mouse Model of Dementia

15:20	Break

	Proffered Papers
15:40		Brian B. Roman, Ph.D., University of Chicago, Chicago, IL, USA In Vitro High Resolution MEMRI Studies of Glucose Activated Rat Pancreas
15:00		Marius Widderoe, Norwegian University of Science and Technology, Trondheim, Normay MEMRI of the Rat Neonatal Hypoxic-ischemic (HI) Stroke Model

16:20	General Assembly: Closing Discussion on MEMRI

16:30	Plenary Lecture 2: Andreas Jacobs, Ph.D., Max-Planck-Institut, Cologne, Germany

17:15	Adjournment

18:00	Dinner

Tuesday, 6 February
08:00 - 09:00	Breakfast

09:00 - 14:00	Yucatan (Progresso), Mexico

	Oral Session 3: Novel MR-based MI Approaches, Jeff Bulte, Ph.D., and Angelique Louie, Ph.D., Moderators
15:30		Chrit T. Moonen, Ph.D., Universite Victor Segalen Bordeaux, Bordeaux, France *The Role of Ultrasound and MR in Transfection and Transgene Expression*
15:50		Eric T. Ahrens, Ph.D., Carnegie Mellon University, Pittsburgh, PA, USA *Cell Tracking Using Fluorochemical Labels And 19F MRI*
16:10		Aravind Arepally, M.D., Johns Hopkins University, Baltimore, MD, USA *MR-trackable microcapsules for MR-guided injection and immunoprotection of cellular therapeutics*
16:30		Robert J. Gillies, Ph.D., University of Arizona, Tucson, AZ, USA Imaging of Tumor pH with a Single Injection of a pH-sensitive MR Contrast Agent Cocktail

	Proffered Papers
16:50		Geralda van Tilborg, M.S., Eindhoven University of Technology, Eindhoven, The Netherlands Avidin Induced Clearance of Biotinylated Paramagnetic Liposomes for Improved MR Molecular Imaging
17:10		Donald Nolting, Vanderbilt University, Nashville, TN, USA Multi-modal Optical and MR Contrast Agents for Use in Vascular and Perfusion Imaging

17:30	General Assembly: Closing Discussion on Current Status of Novel Angles of MRMI Approach

18:00 - 20:30	Dinner

	Oral Session 4: (para) CEST Contrast Agents, Robert Gillies, Ph.D., and Chrit Moonen, Ph.D., Moderators
20:30		Michael T. McMahon Ph.D., Johns Hopkins University , Baltimore, MD, USA *Multi-colored MR Imaging Using CEST Contrast Agents*

	Proffered Papers
20:50		Assaf Gilad, Ph.D., Johns Hopkins University, Baltimore, MD, USA *Detection of MRI Contrast Based on Chemical Exchange Saturation Transfer (CEST) in the Presence of the T2/T2 Contrast Agent Feridex*
21:10		Vikram Kodibagkar, Ph.D., UT Southwestern Medical Center, Dallas, TX, USA A Sensitive Albumin-binding PARACEST Agent for in Vivo Applications
21:30		Claire Billotey, M.D., Ph.D., Hôpital E. Herriot, Lyon, France *Hybrid Gadolinium Oxide Nanoparticles: Multimodal Contrast Agents for in Vivo Imaging*

21:50	General Assembly: Closing Discussion on (para) CEST Contrast Agents

22:00	Adjournment


Wednesday, 7 February
08:00 - 09:00	Breakfast

09:00 - 16:00	Cozumel, Mexico

16:00 - 18:00	Poster Session 2

18:00 - 20:30	Dinner

Thursday, 8 February
08:00 - 09:00	Breakfast

	Oral Session 5: Targeted Contrast Agents, Franca Podo, D.Sc., and Annemie van der Linden, D.Sc., Moderators
08:45		Klaas Nicolay, Ph.D., Eindhoven University of Technology, Eindhoven, The Netherlands Target-specific Contrast Agents for Molecular MRI
09:05		Dmitri Artemov, Ph.D., Johns Hopkins University, Baltimore, MD, USA Developing of Imaging Probes for Targeted MRI of Tumor Cell-Surface Receptors
09:25		Lon J. Wilson, Ph.D., Rice University, Houston, TX, USA MRI-guided Therapy with Superparamagnetic Carbon Nanostructures

	Proffered Papers
09:45		Xudong Huang, Ph.D., Harvard Medical School, Boston, MA, USA Preliminary Studies of a Novel MRI Molecular Probe Targeting Alzheimer's Amyloid
10:05		Gustav J. Strijkers, Ph.D., Eindhoven University of Technology, Eindhoven, The Netherlands Molecular Imaging of Collagen using Bimodal Paramagnetic and Flouorescent Liposomes

10:25	Break

	Proffered Papers
10:40		Gabriella Baio, M.D., University of Genova, Genoa, Italy *Magnetic Resonance Detection at 1.5T of Tumor by Means of Superparamagnetic Antibodies with Two Types of Approach: The Direct and Indirect Magnetic Tumor Labeling*
11:00		Claire Corot, Ph.D., Guerbet Research Roissy, France Comparison of Gadolinium and USPIO Folate Compounds on the Targeting of Tumor Folate Receptors
11:20		Vinod Kaimal, M.S., Cincinnati Childrens Hospital, Cincinnati, OH, USA MRI of Targeted Delivery of Saposin C and USPIO to tumor Cells in Vivo Using Liposomes

11:40	General Assembly: Closing Discussion on Targeted Contrast Agents

12:20	Lunch

	Oral Session 6: Tracking of Actively Labeled Cells (Immune Cells, Stem Cells), Tom Chih-Chuang Hu, Ph.D., and Youssed Wadghiri, Ph.D., Moderators
14:00		Erik M. Shapiro, Ph.D., Yale University, New Haven, CT, USA *Sizing up Cellular MRI with Micron Sized Iron Oxide Particles*
14:20		Anna V. Moore, Ph.D., Massachusetts General Hospital, Charlestown, MA, USA *In vivo tracking of transplanted pancreatic islets*
14:40		Claire Billotey, M.D., Ph.D., Hôpital E. Herriot, Lyon, France *MRI tools for in-vivo tracking of immune cells*

	Proffered Papers
15:00		Piotr Walczak, M.D., Johns Hopkins University, Baltimore, MD, USA Applicability of Bioluminescence and MRI for Monitoring Cell-Based Therapy of Demyelination
15:20		Sergey Magnitsky, Ph.D., University of Pennsylvania, Philadelphia, PA, USA In Vivo Labeling of Neurons and Astrocytes after Neonatal Injection Oxide Particles

15:40	Break

16:00		Paula J. Foster, Ph.D., Robarts Research Institute, London ON, Canada Monitoring Cellular Responses in Experimental Models of Inflammation
16:20		Nicolau Beckmann, Ph.D., Novartis Pharma AG, Basel, Switzerland Imaging of Macrophage Infiltration: Opportunities for Drug Research

	Proffered Paper
16:40		Anna Sotnikova, University Clinics Schleswig-Holstein, Kiel, Germany NeoHepatocytes Labeled in Vitro with Combination of Iron Oxide Nanoparticles and Quantum Dots

17:00	General Assembly: Closing Discussion on Cell Labeling

19:00	Closing Dinner

Friday, 9 February: Departure to Airport

The International Society for Magnetic Resonance in Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.