Last updated Thursday, 04 September 2008
 

Friday November 10th   15:00-19:00 Registration and Poster Setup   18:00 Reception   19:15 Dinner   Saturday November 11th 07:00 Registration and Poster Setup   07:00 Breakfast   Session 1:     The Role of MRS in the Clinic, Chair:  Andrew Maudsley, Ph.D. 08:30 Welcome   08:40 “Biochemistry for in vivo MRS” Ognen Petroff, M.D., Yale University, New Haven, CT, USA   09:20 “Translational Research Initiatives for MRS of Cancer” Mike Garwood, Ph.D., University of Minnesota, Minneapolis, MN, USA   09:50 “31P MRS of the Heart” Paul Bottomley, Ph.D.,  John’s Hopkins University, Baltimore, MD, USA   10:10 “Predicting Treatment Response for Non-Hodgkin’s Lymphoma - A Multi-institutional MRS Study” Fernando Arias-Mendoza, M.D., Ph.D., Columbia University, New York, NY, USA   10:30 Break   Session 2:     Spectral Analysis and Quantitation,  Chair: Mike Garwood, Ph.D. 10:50 "jMRUI Quantitation Methods & Application to MRS, MRSI & HRMAS-NMR" Danielle Graveron-Demilly,  Université Claude Bernard, Lyon, France   11:30 "Error Estimation - Role of CRB's in a Semiparametric Context" Dirk van Ormondt, Delft University of Technology, Netherlands   12:00 “Spectral Analysis Using LCModel” Pierre-Gilles Henry, Ph.D.,  University of Minnesota, Minneapolis, MN, USA   12:30 Adjournment   13:00 Lunch   Session 3:     Spectral Analysis and Quantitation,  Chair:  Roland Kreis, Ph.D. 14:15 “MRS Quantitation Methods” Peter Barker, D. Phil., John’s Hopkins University, Baltimore, MD, USA   14:55 Proffered paper - “Constrained Recursive Adaptive Hankel Singular Value Decomposition Algorithm for MRS Data Processing” X. Wang, J-H. Lee,  University of Cincinnati, OH   15:15 Proffered paper - “Tissue Specific Signal Analysis in Multiple Sclerosis using bootstrapping of Short Echo-time 1H 3DMRSI at 3T” H. Ratiney, D. Pelletier, University of California, San Francisco, CA   15:35 Proffered paper -  “Polynomial Fitting Adapted Volumetric Metabolite Image Reconstruction” Y. Bao, A.A. Maudsley, University of Miami School of Medicine, FL   15:55 Break   Session 4:     Spectral Analysis Challenge and Poster Viewing,  Chair: Truman Brown, Ph.D. 16:15 - 17:45 Using a poster presentation format this session will present results from several groups for analysis of several in vivo spectra. The selected spectra will be made available by the workshop organizers and will consist of multinuclear spectra, obtained with different parameters and of differing quality. It is anticipated that the presentations will demonstrate flexibility and performance of different spectral fitting algorithms. (For information on contributing sample data or participation, please contact Truman Brown).   19:15 Dinner Sunday November 12th 07:00 Registration and Poster Setup   07:00 Breakfast   Session 5:     Multi-Dimensional MRS Analysis,  Chair: Peter Barker, D. Phil. 08:00 “Multivariate Analysis of Spectra” Truman Brown, Ph.D.,  Columbia University, New York, NY, USA   08:40 “Integrated Data Acquisition and Processing” Roland Kreis, Ph.D., University of Bern, Switzerland   09:20 “Analyzing Spatial Data” Hoby Hetherington, Ph.D., Albert Einstein College of Medicine, New York, NY, USA   09:50 Proffered paper - “Measurements of T2 of J-coupled Metabolites in the Human Brain” DK Deelchand, M Marjanska, K Ugurbil, PG Henry, University of Minnesota, Minneapolis, MN   10:10 Proffered paper - “PCNSA for NMR Spectroscopy Breast Tissue Classification” M.T. Wenzel, B. Merkel, M. Althaus, H-O. Peitgen, MeVis Research GmbH, Bremen, Germany   10:30 Break   Session 6:     Data Processing Methods for MRSI,  Chair: Hoby Hetherington, Ph.D. 10:50 “Water Referencing for MRSI” Dan Spielman, Ph.D., Stanford University, Stanford, CA, USA   11:30 “Increased Efficiency in MRSI Combining PEPSI and Parallel Imaging” Stefan Posse, Ph.D., University of New Mexico, Albuquerque, NM, USA   12:10 Proffered paper - “Applications of Water Reference Data Acquisition in 1H MRSI” C. Domenig, A.A. Maudsley, University of Miami, Miami, FL   12:30 Adjournment   13:00 Lunch   Session 7:      MRSI Classification and Interpretation,  Chair: Dan Spielman, Ph.D. 14:15 “Brain Metabolite Mapping in Whole Brain” Andrew Maudsley, Ph.D.,  University of Miami, Miami, FL, USA   14:55 “Tissue Classification Methods for MRI and MRSI” Patrick Krooshof, M.D.,  Radboud University, Nijmegen, Netherlands   15:25 Proffered paper - “MRI and MRSI based multiclass LS-SVM classification using class probabilities and feature selection” J. Luts¹, A. Heerschap², J.A.K. Suykens¹, S. Van Huffel¹, ¹Katholieke Universiteit Leuven, Belgium and ²University of Nijmegen, The Netherlands   15:45 Proffered paper - “Towards an Automatic Identification of Tumor Regions in in vivo MR Spectroscopy Data from the Prostate” - not available E. Weiland1, T. Scheenen2, S. Roell1, J. Futterer2, P. van Hecke3, M. Lemort4, P Bachert5, H-P. Schlemmer6, J. Lu7, D. Broome8, G. Villeirs9, J. Barentsz2, A. Heerschap2, 1Siemens Medical Solutions, Germany, 2Radboud University Nijmegen, Netherlands; 3Katholieke Universiteit Leuven, Belgium; 4Jules Bordet Institute, Belgium; 5German Cancer Research Institute, Germany; 6University of Tuebingen, Germany; 7Shanghai Changhai Hospital, China; 8Loma Linda University, USA; 8University Hospital Ghent, Belgium   16:05 Break Session 8:      “Practical Tips” Presentations and Poster Viewing,  Chair: Brian Soher, Ph.D.   This oral session will be held in parallel with a poster session. The presentations will review practical topics of interest to users of specific MR instruments. Speakers will be asked to review manufacturer-specific implementation issues, including for example: best shimming methods; available MRS pulse sequences from the manufacturer; research pulse sequences available from other users; MRS processing tools on the instrument; how to get the data off the MR instrument; data formats and off-line processing options.   16:15 Bruker Robin de Graaf, Ph.D.   16:40 GE Dan Spielman, Ph.D.   17:05 Phillips Peter Barker, D. Phil.   17:30 Siemens Stefan Posse, Ph.D.   17:55 Varian Hoby Hetherington, Ph.D. 18:20 Adjournment   19:15 Dinner   Monday November 13th   07:00 Registration and Poster Setup   07:00 Breakfast     Session 9:      MRS Acquisition and Interpretation Considerations,  Chair: Stefan Posse, Ph.D.   08:00 “1H MRSI Reproducibility, Variability, and Interpretation” Norbert Schuff, Ph.D., University of California San Francisco, CA, USA   08:40 “Approaches to Spectral Simplification” Hoby Hetherington, Ph.D., Albert Einstein College of Medicine, New York, NY, USA   09:20 Proffered paper - “Automating “the other” evaluation of the MR spectrum – a pattern recognition approach in the classification of MRSI data quality” B.H. Menze1,2, B.M. Kelm1, M-A. Weber3, P. Bachert2,3, F.A. Hamprecht1,2, 1,2University of Heidelberg, 3German Cancer Research Center, Heidelberg, Germany  09:40 Proffered paper “Spectral Separation Resolves Partial Volume Effect of MRSI as Demonstrated on Brain Tumor Scans” Y. Su1, S.B. Thakur2, K. Sasan2, S. Du3, P. Sajda3, W. Huang2, L.C. Parra1. 1The City College of the City University of New York; 2Memorial Sloan-Kettering Cancer Center; 3Columbia University, New York, NY   10:00 "Frequency-Swept NMR" Mike Garwood, Ph.D., University of Minnesota, Minneapolis, MN, USA   Session 10:    Nuts and Bolts of MRS Data Processing,  Chair: Dirk van Ormondt, Ph.D.   10:40 “The New DICOM Standard and MRS” David Clunie, M.D.,  Princeton Radiology Pharmaceutical Research, Princeton, NJ, USA   11:10 “Spectral Simulation: Applications in Spectral Acquisition and Analysis” Brian Soher, Ph.D.,  Duke University, Durham, NC, USA   11:40 Proffered paper - “Correcting for Center Frequency Variations in MRSI Data Using the Unsuppressed or Partially-suppressed Water Signal” L.P. Panych, J.R. Roebuck, N-K. Chen, Harvard Medical School, Boston MA   12:00 Proffered paper - “Processing of Chemical Shift Imaging Data of the Human Brain on a 7T Ultra High Field Magnetic Resonance Scanner” S. Sammet1, R.M. Koch1, J. Murdoch2, M.V. Knopp1, 1The Ohio State University, Columbus, OH, 2Philips Medical Systems, Cleveland, OH   12:20 “Summary” Truman Brown, Ph.D., Columbia University, New York, NY, USA   12:30 Adjournment   13:00 Lunch