Program

 
DAY 1 Friday, 07 November 2008
14:00 Registration
   
18:00 Dinner
   
19:30 Very Basics of MRS and Metabolism
Graeme F. Mason, Ph.D., Yale University School of Medicine, New Haven, CT, USA
Robin A. de Graaf, Ph.D., Yale University School of Medicine, New Haven, CT, USA
Kelvin O. Lim, M.D.,
University of Minnesota, Minneapolis, MN, USA
   
DAY 2 Saturday, 08 November 2008
   
07:00 Breakfast
   
08:30 Opening Remarks
Kelvin O. Lim, M.D.,
University of Minnesota, Minneapolis, MN, USA
   
08:45 Overview of Glutamate and GABA in Neurological and Psychiatric Disorders
Joseph Callicott, M.D.,
Clinical Brain Disorders Branch, National Institute of Mental Health, Bethesda, MD, USA
   
09:30 Relationships of Glutamate, GABA and Families of Neurotransmitters
Robert G. Shulman, Ph.D., Yale University School of Medicine, New Haven, CT, USA
   
10:15 Break
   
10:30 Interleaving of Imaging Modalities to Understand Function
Mark Mintun, M.D., Washington University of St. Louis, St. Louis, MO, USA
   
11:15 Lunch
   
12:30 Challengers for Quantification
Truman R. Brown, Ph.D., Columbia University, New York, NY, USA
Ivan Tkac, Ph.D., University of Minnesota, Minneapolis, MN, USA
   
  Proffered Papers
13:40 The Use of MR Spectroscopy to Assess Neurogenesis in an Animal Model for Chronic Mild Stress
Adriaan Campo,
Bio-Imaging Lab; University of Antwerp; Groenenborgerlaan 171, B-2020 Antwerp, Belgium
   
14:00 Break
   
14:20 Technical Approaches to Measure GABA & Glutamate
Robin A. de Graaf, Ph.D., Yale University School of Medicine, New Haven, CT, USA
Peter S. Allen, Ph.D., University of Alberta, Edmonton, AB, Canada
Lana Kaiser, Ph.D., Univerisity of California, San Francisco, San Francisco, CA, USA
   
  Proffered Papers
16:20 In Vivo Human Brain γ-Aminobutyric Acid Detection by 1H MRS at 3.0T with the J-Editing Technique: Sensitivity Enhancement, Macromolecule Contamination and Test-Retest Reliability
Dikoma C. Shungu, Ph.D., Cornell University, New York, NY, USA
16:35 Peak Detection of Glutamate and GABA in Human Brain at 4.7T Using Highly Resolved 2D Constant Time 1H MRS
Hidehiro Watanabe, Ph.D., National Institute for Environmental Studies, Tsukuba, Ibaraki, Japan
   
16:50 Coffee and Posters
   
18:00 Dinner
   
19:15 Mood and Anxiety Disorders
Gerard Sanacora, M.D., Connecticut Mental Health Center, New Haven, CT, USA
Nicholas J. Coupland, M.B., Ch.B., University of Alberta, Edmonton, AB, Canada
John D. Port, M.D., Ph.D., Mayo Clinic, Rochester, MN, USA
   
  Proffered Papers
20:45 Concomitant Changes in Neurotransmitter Levels and in Brain Bioenergetics During the Treatment of Major Depressive Disorder
Dan V. Iosifescu, M.D., Massachusetts General Hospital, Boston, MA, USA
20:58 Assessment of GABA and Glutamate/Glutamine at 3.0T in Chronic Fatigue Syndrome, Major Depressive Disorder and Healthy Volunteers
Chris Kelly, M.S., Mount Sinai School of Medicine, New York, NY, USA
21:11 1H MRSI and Cognitive-Behavioral Therapy in Adult OCD
Joseph O'Neill, Ph.D., UCLA, Los Angeles, CA, USA
   
DAY 3 Sunday, 09 November 2008
   
07:15 Breakfast
   
08:00 Spectroscopic Imaging of Neurotransmitters
Stephan Posse, Ph.D., University of New Mexico, Albuquerque, NM, USA - not available
In-Young Choi, Ph.D., Hoglund Brain Imaging Center, University of Kansas Medical Center, Kansas City, KS, USA - not available
Daniel M. Spielman, Ph.D., Stanford University, Stanford, CA, USA
   
10:00 Break
   
10:20 Schizophrenia
Juan R. Bustillo, M.D., University of New Mexico, Albuquerque, NM, USA
Jean Théberge, Ph.D., St. Joseph's Health Care, London, ON, Canada
   
  Proffered Papers
11:38 Metabolite T2 Relaxation Time Abnormalities in Bipolar Disorder and Schizophrenia
David Olson, M.D., Ph.D., Harvard University, Belmont, MA, USA
11:51 Abnormal Glutamatergic Neurotransmission and Neuronal-Glial Interactions in Acute Mania
Dost Ongur, M.D., Harvard University, Belmont, MA, USA
12:04 Altered Metabolism of Membrane Phospholipids in Schizophrenia Subjects Exposed to Herpes Simplex Virus 1
Konasale M. Prasad, M.D., University of Pittsburgh, Pittsburgh, PA, USA
12:17 Cortical Glutamate and Reward Related Ventral Striate Activity - Comparison of Healthy Subjects and Schizophrenics using fMRI-MRS at 3T
Florian Schubert, Ph.D., Phys-Technische Bundesanstalt, Berlin, Germany
   
12:30 Lunch
   
13:30 Free Afternoon
   
17:00 Posters
   
18:00 Dinner
   
19:30 Neurotransmitter Kinetics and fMRS
Brian David Ross, M.D., Ph.D., Huntington Medical Research Institute, Pasadena, CA, USA
Ralph E. Hurd, Ph.D., GE Healthcare, Menlo Park, CA, USA
Douglas L. Rothman, Ph.D., Yale University School of Medicine, New Haven, CT, USA
   
   
DAY 4 Monday, 10 November 2008
   
07:15 Breakfast
   
08:00 Substance Abuse
Perry F. Renshaw, M.D., Ph.D., McLean Hospital, Belmont, MA, USA
Dieter J. Meyerhoff, Ph.D., DVA Medical Center, San Francisco, CA, USA
Graeme Mason, Ph.D., Yale University School of Medicine, New Haven, CT, USA
   
  Proffered Papers
09:30 Impact of Depression on Cerebral Glutamate and Cognitive Function in Abstinent Methamphetamine Users (AMU)
Osama Abulseoud, M.D., University of Southern California, Los Angeles, CA, USA
09:45 Examining the Association between Frontal Lobe GABA Metabolite Levels and Binge Alcohol Consumption: A 4.0 Tesla Magnetic Resonance Spectroscopy Study
Marisa M. Silveri, Ph.D., McLean Hospital, Belmont, MA, USA
   
10:00 Break
   
10:15 Child Psychiatry
Stephen Strakowski, M.D., University of Cincinnati, Cincinnati, OH, USA - not available
Jeffrey A. Stanley, Ph.D., Wayne State University, Detroit, MI, USA
   
  Proffered Paper
11:45 Subcortical 1H MRSI Abnormalities in Childhood Autism
Joseph O'Neill, Ph.D., UCLA, Los Angeles, CA, USA
   
12:00 Summary
   
12:30 Adjournment and Lunch
   
 

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