ISMRM23 - Wake Up & Take a Deep Breath!

ISMRM & ISMRT Annual Meeting & Exhibition • 03-08 June 2023 • Toronto, ON, Canada

Wake Up & Take a Deep Breath!

Sunrise Course

ORGANIZERS: Nandita deSouza, Scott Reeder

Monday, 05 June 2023

713A/B

07:00 - 08:00

Moderators: Kieren Hollingsworth & Mary Neal

Skill Level: Intermediate to Advanced

Session Number: S-M-03

CME and CE Credit

Session Number: S-M-03

Overview
In this session, the application of MRI to assess two important pulmonary topics will be addressed: vaping-associated lung injury and long term pulmonary sequelae of COVID-19 pneumonia.

Target Audience
Physicians and researchers interested in the development and application of advanced MRI methods to assess lung disease.

Educational Objectives
As a result of attending this course, participants should be able to:
- Identify the main MRI techniques used to assess lung disease;
- Describe the basic pathophysiology of vaping-associated lung injury; and
- Explain the use of hyperpolarized gas MRI to assess sequela of COVID-19 pneumonia.

07:00		Exposing Vaping-Associated Lung Injury View Presentation Video Mark Schiebler Keywords: Contrast mechanisms: Hyperpolarized MR (Gas), Body: Lung, Cross-organ: Inflammation Electronic Vaping Associated Lung Injury (EVALI) and Electronic Nicotine Delivery Systems (ENDS) deliver addictive biologically active particulates (one micron in size) directly into the blood stream. This is accomplished by a battery powered heated filament that vaporizes the addictive agent along with one or more carrier substances. We are at the beginning stages of understanding the biological effects of these new delivery devices and if they will decrease the incidence of lung cancer in their users compared with cigarettes. Pilot data suggests that ENDS users have a disruption in their ability to match ventilation with perfusion at the arteriolar level.
07:30		Hyperpolarized Gas MRI helps explain long-covid View Presentation Video Grace Parraga Keywords: Body: Respiratory, Contrast mechanisms: Hyperpolarization, Contrast mechanisms: fMRI We will explore new fundings using pulmonary functional MRI using inhaled 129Xe gas that help explain long-COVID in patients.