ISMRM22 - Imaginarium: Engineering Inclusive Clinical Trials

Joint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting • 07-12 May 2022 • London, UK

Imaginarium: Engineering Inclusive Clinical Trials

Onsite Tutorial

ORGANIZERS: Udunna Anazodo, Kathryn Keenan, Richard Bowtell

Saturday, 07 May 2022

S11 (Breakout B)

08:00 - 12:00

Moderators:
Imaginarium: Engineering Inclusive Clinical Trials I: Reimagining Inclusive Clinical Studies: Julie DiCarlo
Imaginarium: Engineering Inclusive Clinical Trials IV: Data Management Software Tutorial: Sairam Geethanath

Skill Level: Basic to Intermediate

Session Number: ET-02

Session Number: ET-02

Overview
There are several barriers to research participation among individuals from marginalized, rural, and low socioeconomic communities, including specific individual challenges, collective negative views on research held by a community, and barriers imposed by the research design and management. This tutorial will introduce practical tools for building inclusive clinical study populations locally and globally, and within the current research infrastructure (funding, centralized research facilities, management, regulation, etc.). Approaches to reduce barriers to participation in clinical studies including regulatory policies and examples of community-based
programs that enhance participation will be highlighted. Social innovation ideas that create meaningful and lasting solutions will be introduced as a potential framework for creating practical diverse study populations.

Target Audience
Radiologists, scientists, medical physicists, engineers, and technologists at
all career levels.

Educational Objectives
As a result of attending this course, participants should be able to:
- Recognize challenges in creating diverse and inclusive clinical study populations;
- Show opportunities for innovation in study design and management to promote inclusive research participation;
- List practical foundational tools for creating richer study populations; and
- Explain how social innovation concepts can be utilized to strengthen inclusive clinical study designs.

	Imaginarium: Engineering Inclusive Clinical Trials I: Reimagining Inclusive Clinical Studies
08:00		Designing Inclusive Clinical Trials & Study Populations View the Presentation Karina Quiaoit Biomedical research routinely produce broad claims about behavior and body function/dysfunctions based on data drawn largely from western, educated, industrialized, rich and democratic communities, often assuming there is little variation across populations, although the highest burden of chronic diseases resides in low-income and low-resourced communities. Neglecting such populations restricts our ability to characterize the full disease spectrum and understand complex disease pathogenesis, further exacerbating disparities across populations. With the introduction of novel imaging technologies aimed at enabling access to neglected populations, it is now time to reimagine inclusive imaging studies and clinical trials to advance discoveries with far reaching implications.
08:30		OurBrainsCAN: A Patient Registry for Inclusive Participatory Clinical Research Video Unavailable Laura Gonzalez, Ysabel Macdonald
	Imaginarium: Engineering Inclusive Clinical Trials II: Regulatory Frameworks to Enhance Inclusive Research
09:00		Creating a Regulatory Framework for Imaging Studies in Africa View the Presentation Ernesta Meintjes
09:30		Biomedical Engineering Innovations for Inclusive Imaging Trials TBD
10:00		Break & Meet the Teachers
	Imaginarium: Engineering Inclusive Clinical Trials III: Building Richer Clinical Trial Data Through Management
10:30		Data Acquisition & Harmonization for Multi-Center Studies View the Presentation Gareth Barker
11:00		Pragmatic Solutions and Technologies for Decentralized Clinical Imaging Trials TBD
	Imaginarium: Engineering Inclusive Clinical Trials IV: Data Management Software Tutorial
11:30		Flywheel: A Comprehensive Platform for Clinical Data Management Video Unavailable Can Akgun
12:00		Cloud-Enabled Imaging Informatics & Analytics Solutions for Inclusive Imaging Trials TBD