Advances in Noninvasive Structure-Function Assessment of Musculoskeletal Tissues
Member-Initiated Symposium
Tuesday, 10 May 2022
ICC Capital Hall 2
16:45 - 18:45
Session Number: MIS-03
Organizers
David Reiter
Corey Neu
Overview
This symposium focuses on medical and MR imaging-based experimental characterization, computational modeling, and the potential synergies among these fundamental ingredients, to assess the structure-function of musculoskeletal tissues. The goal is to promote cross-fertilization of ideas and collaborative experimental and numerical efforts toward progressing the overall field of research on tissues, and in the context of diseases, including, but not limited to degeneration, atrophy, fibrosis, and arthritis. Emphasis will be placed on novel or emerging image-based techniques in mechanical characterization and visualization, microstructure and tissue component imaging; computational and experimental approaches at all length scales (cellular, tissue and joint system levels); multi-modal imaging modalities; and the ability for noninvasive imaging methods to probe the earliest stages of disease pathogenesis or regeneration, anticipating the evaluation and appropriate delivery of new therapeutics.
Target Audience
Basic science and clinical communities with an interest in new imaging biomarkers to probe structure-function relationships in healthy/diseased muscul
Educational Objectives
As a result of attending this course, participants should be able to:
1. Fundamental knowledge of emerging pulse sequence design and imaging methods to quantify the structure and function of MSK tissues with emphasis on validity, reproducibility, and vendor specificity.
2. Exposure to emerging analytical frameworks pairing structure-function assessment in MSK tissues over a range of length scales.
3. Applied knowledge linking new imaging methods with their ability to probe early changes in disease pathogenesis and treatment effectiveness.
4. Value and challenges in translation of structure-function methods for clinical utilization.
16:45
Tendon Structure Function
Video Unavailable
Jennifer Zellers
Washington University, United States
17:05
Strain Rates Along & Perpendicular to the Fiber are Heterogeneously Distributed Along the Length of Lower Leg Muscles During Dynamic Contractions
Video Unavailable
Melissa Hooijmans
Amsterdam University Medical Center, Netherlands
17:25
A MATLAB Toolbox for DTMRI-Based Muscle Structure-Function Analysis
Video Unavailable
Bruce Damon
University of Illinois, United States
17:45
Role of the Extracellular Matrix in Age-Associated Strength Loss: Combining Advanced Functional and Microstructure MRI with Biochemistry & Modeling
Video Unavailable
Shantanu Sinha
University of California, San Diego, United States
The International Society for Magnetic Resonance in Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
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