ISMRM22 - Complementing MRI with Other Modalities: Hardware & Method Development: Multimodal Systems in Clinical Cancer Care

Joint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting • 07-12 May 2022 • London, UK

Complementing MRI with Other Modalities: Hardware & Method Development: Multimodal Systems in Clinical Cancer Care

Sunrise Course

ORGANIZERS: Candace Fleischer, Natalia Petridou, Maxime Guye, Özlem Ipek

Tuesday, 10 May 2022

ICC Capital Hall 1

08:00 - 09:00

Moderators: Hui Mao

Skill Level: Basic to Advanced

Session Number: S-Tu-08

Session Number: S-Tu-08

Overview
This educational course provides an overview of opportunities and challenges involved in combining other modalities with MRI, with a focus on in-bore systems including EEG, TMS, ultrasound, PET, linac, and motion tracking hardware.

Target Audience
Scientists and clinicians who want to learn about hardware and methods involved in multimodal imaging.

Educational Objectives
As a result of attending this course, participants should be able to:
- Summarize the state-of-the-art technical aspects of multimodal MRI;
- Recognize the challenges and opportunities with multimodal systems and tools that can be combined with MRI; and
- Identify the engineering aspects involved in EEG, TMS, ultrasound, motion tracking, PET, and linacs.

	08:00		How to add values of PET in hybrid PET/MRI in cancer staging and prognostic prediction? View the Presentation Tiffany Ting-Fang Shih PET/MRI provides multi-parametric evaluation in cancer staging and serve as hybrid biomarkers. Hybrid imaging biomarkers may have association with pathological prognostic factors and survival. In endometrial cancer, SUVmax/ADCmin represented higher tumor metabolism and cellularity; and correlated with pathological prognostic factors. In pancreatic ductal adenocarcinoma, hybrid biomarker (MTV/ADCmin) showed negative correlation in progression-free survival. Patients with higher values of TLG or TLG/Peak ratio have shorter overall survival. In esophageal cancer, MTV/ADCmin may predict overall survival. In further, PET can make MR reading easier for lymphadenopathy and systemic staging. PET/MR can pave to precision medicine and better convenience for the aging society.
	08:30		MR Linac View the Presentation Marielle Philippens The integration of an MRI system and a linear accelator is challenging due to magnetic and radiofrequncy interference of both systems and the attenuation of the photon beam with the magnet. Magnetic fields up to 1.5T have been used. These systems offer online adaptation of the target, gating and real-time tracking.