Joint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting • 07-12 May 2022 • London, UK

2022 Joint Annual Meeting ISMRM-ESMRMB and 31st ISMRT Annual Meeting

Weekday Course

fMRI Connectomics

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fMRI Connectomics
Weekday Course
ORGANIZERS: Wei-Tang Chang, Shin-Lei Peng, Derek Jones, Alex T. L. Leong
Wednesday, 11 May 2022
ICC Capital Hall 1
16:45 -  18:45
Moderators: 
All Sections: Joanes Grandjean & Stefan Posse
Skill Level: Intermediate to Advanced
Session Number: W-06
 

Session Number: W-06

Overview
This session will provide an overview of the present and future developments of fMRI connectomics spanning works from animal and human brains, including its neural basis, analysis methods, applications in healthy and diseased brains, and opportunities and potential challenges in this evolving research landscape.

Target Audience
Scientists, clinicians, and researchers who are interested in functional connectivity and its associated applications in healthy and diseased brains.

Educational Objectives
As a result of attending this course, participants should be able to:
- Describe the state-of-the-art methodologies of fMRI connectomics;
- Discuss the neural basis underlying functional connectivity;
- Apply the approaches of functional connectivity in preclinical and clinical research; and
- Recognize the opportunities and limitations/challenges of fMRI connectomics.
 

    fMRI Connectomics: From Basic to Frontier
16:45   Functional Connectomics: State-of-the-Art Developments in Methodologies & Analysis Techniques

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Li-Wei Kuo
In this educational talk, I will introduce the methodologies and analysis approaches of functional MRI (fMRI) data for mapping the functional connectomics. The methods to calculate the functional connectivity using resting-state or task-based fMRI data and how it can be used for deriving the brain network metrics using graph theoretical analysis or other computational methods will be reviewed. Furthermore, recent technological advances for mapping the functional connectomics and their use on clinical and cognitive neuroscience applications will be also introduced and discussed.
17:15   Neural Basis of Functional Connectomics: Insights from Animal Models & Human Brains

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Zhifeng Liang
Resting-state fMRI and resting-state functional connectivity have been widely utilized for more than two decades. However, the neural basis of functional connectivity remains an open question. In this talk, we will first review techniques that can be utilized to address this issue, such multimodal fMRI and optical imaging methods. Next we will review the neural basis of spontaneous hemodynamic signals at the local level, and then the neural basis of long-range functional connectivity. Importantly, we will further discuss how arousal states and the neuromodulatory system further complicates our understanding of the neural basis of functional connectivity.    
    fMRI Connectomics: From Bench to Bedside
17:45   Bridging the Gap in Functional Connectomics Research: From basic Science to Clinical Studies

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Shella Keilholz
Resting state fMRI studies in humans can be difficult to interpret because the BOLD signal is affected by neural activity, metabolism, and hemodynamics. Multimodal preclinical studies in rodents can guide the interpretation of resting state fMRI studies in humans. This educational course will describe features of rs-fMRI that are conserved across species, compare and contrast acquisition and analysis methods, and describe tools that can be used for investigating the neurophysiology behind rs-fMRI in rodents.
18:15   Opportunities & Challenges in the Rapidly Evolving Landscape of Functional Connectomics Research

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Peter Zeidman

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