Joint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting • 07-12 May 2022 • London, UK

2022 Joint Annual Meeting ISMRM-ESMRMB and 31st ISMRT Annual Meeting

Weekend Course

Machine Learning: From Mathematical Models to Clinical Practice

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Machine Learning: From Mathematical Models to Clinical Practice
Weekend Course
ORGANIZERS: Hao Huang, Janine Lupo, Dong Liang, Fang Liu
Saturday, 07 May 2022
ICC Capital Hall 2
08:00 -  12:00
Moderators: 
ML Math to Clinic I: Jana Hutter
ML Math to Clinic II: Virendra Mishra
ML Math to Clinic III: Kerstin Hammernik
ML Math to Clinic IV: Esin Ozturk-Isik
Skill Level: Basic to Advanced
Session Number: WE-04
 

Session Number: WE-04

Overview
In this session, we will cover mathematical models that serve as the theoretical foundation of machine learning and provide practical guidelines on how to get started from both a technical and clinical point of view. Researchers and clinicians will learn how to apply basic and more advanced machine learning approaches to accelerate MRI acquisition, enhance image analysis, automate clinical workflows, and predict outcomes and prognosis.

Target Audience
Researchers and clinicians interested in learning more about: 1) the nuts and boltsa behind machine learning; 2) how to get started by choosing appropriate models for different tasks; and 3) its unique potential and limitations when applied in the clinic.

Educational Objectives
As a result of attending this course, participants should be able to:
- Define the mathematical models underlying machine learning;
- Choose the appropriate model for their particular research question;
- Describe example applications in MRI where machine learning can be used;
- Recognize limitations and challenges of using machine learning in emerging applications; and
- Discuss the potential clinical impact of machine learning on the field of MRI.
 

    ML Math to Clinic I
08:00 Fundamentals of Machine & Deep Learning

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Jong Chul Ye
In this talk, we will briefly review the current trends of deep learning and explain how they have been employed in MR imaging. In particular, we review the principles of Transformer, generative adversarial nets, optimal transport, cycleGAN,  noise2void, noise2score, and score-based diffusion model. MR application of these methods will be also reviewed. 
08:25   Machine Learning for Protocoling & Radiological Workflows

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Susan Sotardi
 Synopsis:
    ML Math to Clinic II
08:50 Deep Learning for Image Acquisition & Reconstruction

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Matthew Rosen
The availability of inexpensive GPU-based compute has opened the door to new strategies for the acquisition and the reconstruction of highly-undersampled imaging data. We have been developing neural network deep learning based approaches such as AUTOMAP and to leverage scalable-compute and significantly reduce the need for precision scanning hardware. These approaches are very valuable in low SNR regimes like millitesla MRI or high-b value DWI. We describe here the AUTOMAP formalism and how it can be used to improve reconstruction SNR and accuracy as well as open up the possibility of new sampling strategies.
09:15 Unsupervised Deep Learning for Fast Imaging: From DAE to Generative Model

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Qiegen Liu
Recently studies have witnessed great progresses of generative modeling in medical imaging reconstruction like fast MRI and low-dose CT, etc. Particularly, the series of works from denoising autoencoders to denoising score matching as well as score-based diffusion model exhibits great promising performance in reconstruction quality and algorithm robustness. In this talk, we will first review the relationship among these algorithms. Then, we reveal the underlying ideas that substantially contribute to the performance improvements, such as constructing high-dimensional space and conducting on data samples with different geometrical properties.
  09:40   Break & Meet the Teachers
 
    ML Math to Clinic III
10:05   Special Topics I: Unsupervised vs. Supervised Learning

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Valentina Pedoia
10:30 Vision Transformers in Medical Imaging

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Tolga Cukur
Deep learning models have been swiftly established as state-of-the-art in recent years for difficult medical image formation and analysis tasks such as reconstruction, synthesis, super-resolution and segmentation. A critical design consideration for model architectures is the capacity to account for representation errors that comprise both locally- and globally-distributed elements. While convolutional models with static local filters have been widely adopted due to their computational benefits, they lack in sensitivity for contextual or anomalous features. Instead, the recently emerging vision transformers are equipped with global attention operators as a universal mixing primitive for minimizing representation errors in diverse medical imaging tasks.  
    ML Math to Clinic IV
10:55   Application in the Clinic: Predicting Phenotypes, Prognosis & Outcome

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Yun Peng
11:20   Clinical Outlook: Pitfalls & Promises

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Xiaoying Wang

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The International Society for Magnetic Resonance in Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.