ISMRM & ISMRT Annual Meeting & Exhibition • 03-08 June 2023 • Toronto, ON, Canada
07:00 |
Blood-Brain Barrier Dysfunction in Neurological Diseases
Danny Wang
Keywords: Neuro: Brain function, Contrast mechanisms: Perfusion, Image acquisition: Quantification Blood-brain barrier (BBB) plays a critical role in the delivery of oxygen and nutrients to the brain, clearance of toxic metabolites, and protection of the central nervous system (CNS) from infection. Impaired BBB function is implicated in a number of serious CNS diseases, such as multiple sclerosis, stroke, brain tumors, Alzheimer's disease and small vessel disease. Assessment of BBB permeability commonly relies on dynamic contrast enhanced MRI using Gd-based contrast agents. Recently, contrast and non-contrast MRI methods have emerged to assess BBB water exchange. The combination of these MRI methods has revealed the mechanism of BBB dysfunction in neurological disorders. |
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07:30 | Gut Microbiota in Dementia Qin Chen |
The International Society for Magnetic Resonance in Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.