Quiz: Methods to Validate Quantitative Perfusion Measures, Fan

1. Positron emission tomography with O-15 water and Xenon gas CT are considered reference standards for perfusion imaging because...

a. The tracers are freely diffusible across the blood-brain barrier
b. The tracers have short half-lives
c. Established kinetic models exist for quantification of cerebral blood flow
d. a and c
e. a and b

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2. For cerebrovascular patients with long arterial transit times, which acquisition change will most likely improve the accuracy of arterial spin labeling?

a. Decrease the post-label delay
b. Increase the labeling duration
c. Increase the post-label delay

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3. In clinical trials, dynamic susceptibility contrast MRI has been used to stratify stroke patients based on thresholds of...

a. Time-to-maximum delay
b. Cerebrovascular reactivity
c. Relative cerebral blood flow
d. None of the above

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4. Which are necessary to measure cerebrovascular reactivity?

a. Gadolinium contrast injection
b. Multiple brain perfusion states
c. Quantitative perfusion imaging
d. Multiple gas inhalation challenges
e. b, c, and d
f. b and c

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