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Q&A with Xiao-Yong Zhang and Zhongliang Zu

By Mathieu Boudreau

Xiao-Yong Zhang

The August 2017 Editor’s Pick is from Xiao-Yong Zhang and Zhongliang Zu, researchers at Vanderbilt University in Nashville. Their paper presents a newly discovered Nuclear Overhauser Effect (NOE) signal at -1.6 ppm from water. They measured this signal in normal rat brains at 9.4 T, and found that it changed significantly in a rodent tumor model. Using reconstituted phospholipids and cultured cell experiments, they hypothesize that this signal may originate from membrane choline phospholipids. We recently spoke with Xiao-Yong and Zhongliang Zu about their work.  (more…)

By | August 18th, 2017 | Highlights-post, Highlights-QA | Tags: , , , ,

August Highlights

August Cover Art

A dedicated neonatal brain imaging system, by Emer J. Hughes, Tobias Winchman, Francesco Padormo, Rui Teixeira, Julia Wurie, Maryanne Sharma, Matthew Fox, Jana Hutter, Lucilio Cordero-Grande, Anthony N. Price, Joanna Allsop, Jose Bueno-Conde, Nora Tusor, Tomoki Arichi, A. D. Edwards, Mary A. Rutherford, Serena J. Counsell and Joseph V. Hajnal

August Editor’s Picks

(2 + 1)D-CAIPIRINHA accelerated MR spectroscopic imaging of the brain at 7T, by B. Strasser, M. Považan, G. Hangel, L. Hingerl, M. Chmelik, S. Gruber, S. Trattnig and W. Bogner

audioslides : coming soon !

MR imaging of a novel NOE-mediated magnetization transfer with water in rat brain at 9.4 T, by Xiao-Yong Zhang, Feng Wang, Tao Jin, Junzhong Xu, Jingping Xie, Daniel F. Gochberg, John C. Gore and Zhongliang Zu

audioslides

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By | August 11th, 2017 | Highlights-post | Tags:

Q&A with Patrick Schuenke and Moritz Zaiss

                                                               By Brian Chung

Patrick Schuenke

This week we ventured across continents to speak with Drs. Patrick Schünke and Moritz Zaiss, two primary authors of a recent paper from the German Cancer Research Center (DKFZ) in Heidelberg, Germany titled: “Adiabatically Prepared Spin-Lock Approach for T1ρ-Based Dynamic Glucose Enhanced MRI at Ultrahigh Fields.” In this paper, the authors developed an NMR method for imaging glucose using an ultrahigh field MR scanner and a spin-lock approach to gain sensitivity to chemical exchange. At ultrahigh field strengths, distinct artifacts appear predominantly resulting from RF field inhomogeneities. Thus, adiabatic pulses were implemented to enable the application of spin-lock MRI at fields such as 7T. This adiabatic spin-lock approach is explained, its feasibility for application in vivo at 7T is verified, the technique’s sensitivity to glucose is investigated, and a first proof of concept of spin-lock based glucose imaging for the detection of cancer in humans is presented. (more…)

Q&A with Zhe Liu and Pascal Spincemaille

Zhe Liu

By Pinar Ozbay

It is our pleasure to present one of the Editor’s picks for July, Preconditioned Total Field Inversion (TFI) Method for Quantitative Susceptibility Mapping (QSM), from Cornell University. In this work Zhe Liu, Pascal Spincemaille and colleagues proposed an algorithm which allows mapping of tissue magnetic susceptibility in regions with large dynamic susceptibility ranges, such as cavities, bones, and hemorrhages in the head. There are two main steps in QSM algorithm which are removal of background fields to calculate the local field, and solving the local field-to-susceptibility problem. The latter is an ill-posed problem by nature, hence is mainly referred to as the step of inverse problem in the literature of QSM. Their method calculates susceptibility maps via ‘total field inversion’, which generalizes those two steps as one optimization problem, and further employs preconditioning to achieve fast convergence.

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