Quiz: Cross Cutting & Emerging Technologies 5

Objectives: Transcranial focused ultrasound is an old idea which has become a clinical reality within recent years. MR image guidance and treatment monitoring are key enablers of focused ultrasound technology for use in the brain. The origins, current state and future roadmap of this technology will be discussed. Given the challenges of accessing the brain and the high cost and limitations of some current approaches, this non-invasive technology has the potential to revolutionize the treatment of many brain disorders.

1. What technology developments occurring between 1950 and 1990 ultimately made the clinical delivery of therapeutic ultrasound through the intact skull feasible?*

Computer technology
CT and MR imaging
FUS phased array technology
All of the above

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2. Which clinical brain indications currently have US FDA approval for treatment with FUS? (at the time of the talk)*

Essential Tremor
Parkinson's Disease
Mesial Temporal Lobe Epilepsy

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3. What role does MR play in the treatment of the brain with FUS?*

Targeting and treatment monitoring (PRF shift thermometry)
Patient Screening
Functional mapping

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4. What role does CT currently play in the treatment of the brain with FUS?*

Estimation of acoustic scattering of skull bone
Estimation of acoustic phase aberration of skull bone, necessary for forming a sharp focal spot
Estimation of intracranial volume

Jump to the relevant part of the video for question 4: