Quiz: DSC-MRI: Acquisition, Boxerman

1) Which of the following is least impactful on relative CBV estimates using single-echo DSC-MRI?

Jump to the relevant part of the video for the above question:

2) All of the following contribute to MR susceptibility contrast except...

A. Time between DSC-MRI samples (TR)
B. Vessel size (diameter)
C. Proton diffusion rate
D. Contrast agent dose (susceptibility difference between the intra- and extra-vascular space)
E. MRI pulse sequence (GRE vs. SE)

Jump to the relevant part of the video for the above question:

3) All of the following techniques help reduce contrast agent leakage effects in DSC-MRI except...

Jump to the relevant part of the video for the above question:

4) All of the following statements are true except...

A. Compliance of DSC-MRI with the standardized brain tumor imaging protocol (BTIP) places constraints on the allocation of contrast agent dose between preload and bolus.
B. Historically, DSC-MRI methodology in the literature has been very consistent.
C. Low flip angle/no preload and intermediate flip angle/preload DSC-MRI techniques have similar CBV accuracy and precision based on simulations and in vivo studies.
D. For BTIP-compliant single-dose DSC-MRI, intermediate flip angle performs poorly compared to low flip angle, especially at 1.5T.
E. Elimination of preload reduces contrast agent dose and eliminates potential error due to variable preload incubation time.

Jump to the relevant part of the video for the above question: