Q&A with Xiao-Yong Zhang and Zhongliang Zu

By Mathieu Boudreau

Xiao-Yong Zhang

The August 2017 Editor’s Pick is from Xiao-Yong Zhang and Zhongliang Zu, researchers at Vanderbilt University in Nashville. Their paper presents a newly discovered Nuclear Overhauser Effect (NOE) signal at -1.6 ppm from water. They measured this signal in normal rat brains at 9.4 T, and found that it changed significantly in a rodent tumor model. Using reconstituted phospholipids and cultured cell experiments, they hypothesize that this signal may originate from membrane choline phospholipids. We recently spoke with Xiao-Yong and Zhongliang Zu about their work. 

By |August 18th, 2017|Highlights-post, Highlights-QA|Comments Off on Q&A with Xiao-Yong Zhang and Zhongliang Zu

August Highlights

August Cover Art

A dedicated neonatal brain imaging system, by Emer J. Hughes, Tobias Winchman, Francesco Padormo, Rui Teixeira, Julia Wurie, Maryanne Sharma, Matthew Fox, Jana Hutter, Lucilio Cordero-Grande, Anthony N. Price, Joanna Allsop, Jose Bueno-Conde, Nora Tusor, Tomoki Arichi, A. D. Edwards, Mary A. Rutherford, Serena J. Counsell and Joseph V. Hajnal

August Editor’s Picks

(2 + 1)D-CAIPIRINHA accelerated MR spectroscopic imaging of the brain at 7T, by B. Strasser, M. Považan, G. Hangel, L. Hingerl, M. Chmelik, S. Gruber, S. Trattnig and W. Bogner

audioslides : coming soon !

MR imaging of a novel NOE-mediated magnetization transfer with water in rat brain at 9.4 T, by Xiao-Yong Zhang, Feng Wang, Tao Jin, Junzhong Xu, Jingping Xie, Daniel F. Gochberg, John C. Gore and Zhongliang Zu


By |August 11th, 2017|Highlights-post|Comments Off on August Highlights

Q&A with Patrick Schuenke and Moritz Zaiss

                                                               By Brian Chung

Patrick Schuenke

This week we ventured across continents to speak with Drs. Patrick Schünke and Moritz Zaiss, two primary authors of a recent paper from the German Cancer Research Center (DKFZ) in Heidelberg, Germany titled: “Adiabatically Prepared Spin-Lock Approach for T1ρ-Based Dynamic Glucose Enhanced MRI at Ultrahigh Fields.” In this paper, the authors developed an NMR method for imaging glucose using an ultrahigh field MR scanner and a spin-lock approach to gain sensitivity to chemical exchange. At ultrahigh field strengths, distinct artifacts appear predominantly resulting from RF field inhomogeneities. Thus, adiabatic pulses were implemented to enable the application of spin-lock MRI at fields such as 7T. This adiabatic spin-lock approach is explained, its feasibility for application in vivo at 7T is verified, the technique’s sensitivity to glucose is investigated, and a first proof of concept of spin-lock based glucose imaging for the detection of cancer in humans is presented.

By |July 28th, 2017|Highlights-post, Highlights-QA|Comments Off on Q&A with Patrick Schuenke and Moritz Zaiss

Q&A with Zhe Liu and Pascal Spincemaille

Zhe Liu

By Pinar Ozbay

It is our pleasure to present one of the Editor’s picks for July, Preconditioned Total Field Inversion (TFI) Method for Quantitative Susceptibility Mapping (QSM), from Cornell University. In this work Zhe Liu, Pascal Spincemaille and colleagues proposed an algorithm which allows mapping of tissue magnetic susceptibility in regions with large dynamic susceptibility ranges, such as cavities, bones, and hemorrhages in the head. There are two main steps in QSM algorithm which are removal of background fields to calculate the local field, and solving the local field-to-susceptibility problem. The latter is an ill-posed problem by nature, hence is mainly referred to as the step of inverse problem in the literature of QSM. Their method calculates susceptibility maps via ‘total field inversion’, which generalizes those two steps as one optimization problem, and further employs preconditioning to achieve fast convergence.

By |July 14th, 2017|Highlights-post, Highlights-QA|Comments Off on Q&A with Zhe Liu and Pascal Spincemaille

July Highlights

July Cover Art

Optimization of simultaneous multislice EPI for concurrent functional perfusion and BOLD signal measurements at 7T, by Dimo Ivanov, Benedikt A Poser, Laurentius Huber, Josef Pfeuffer and Kâmil Uludağ

July Editor’s Picks

Adiabatically prepared spin-lock approach for T1ρ-based dynamic glucose enhanced MRI at ultrahigh fields, by Patrick Schuenke, Christina Koehler, Andreas Korzowski, Johannes Windschuh, Peter Bachert, Mark E. Ladd, Sibu Mundiyanapurath, Daniel Paech, Sebastian Bickelhaupt, David Bonekamp, Heinz-Peter Schlemmer, Alexander Radbruch and Moritz Zaiss

audioslides : coming soon !

Preconditioned total field inversion (TFI) method for quantitative susceptibility mapping, by Zhe Liu, Youngwook Kee, Dong Zhou, Yi Wang and Pascal Spincemaille


By |July 7th, 2017|Highlights-post|Comments Off on July Highlights

Q&A with Hua Li and Junzhong Xu

                          By Thijs Dhollander

We sat down across time zones again (Australia in the morning, US east coast late afternoon), this time with Hua Li and Junzhong Xu, first and last author of their recent paper “Impact of transcytolemmal water exchange on estimates of tissue microstructural properties derived from diffusion MRI”. Apart from discussing the paper, we couldn’t resist touching on the topic of social media in research these days, as well as the challenges and peer pressure involved with designing good acronyms for novel methods…

By |June 30th, 2017|Highlights-post, Highlights-QA|Comments Off on Q&A with Hua Li and Junzhong Xu

The most-cited scientific papers of Magnetic Resonance in Medicine

We are pleased to present the list of the five most-cited Magnetic Resonance in Medicine articles from 2014:

1. Uecker, M., Lai, P., Murphy, M. J., Virtue, P., Elad, M., Pauly, J. M., Vasanawala, S. S. and Lustig, M. (2014), ESPIRiT—an eigenvalue approach to autocalibrating parallel MRI: Where SENSE meets GRAPPA. Magn Reson Med, 71: 990–1001. doi: 10.1002/mrm.24751

Combined parallel imaging compressed sensing reconstruction of an abdomen using l1-ESPIRiT as implemented in the BART toolbox. The scan was accelerated seven-fold using variable-density Poisson-disc sampling.
By |June 23rd, 2017|Highlights-post|Comments Off on The most-cited scientific papers of Magnetic Resonance in Medicine

Q&A with Jun Chen and Jiang Du

BY Blake Dewey

Jun Chen

I recently had the pleasure of chatting with Drs. Jun Chen and Jiang Du about their recent MRM manuscript entitled “Measurement of Bound and Pore Water T1 Relaxation Times in Cortical Bone Using Three-Dimensional Ultrashort Echo Time Cones Sequences”. We came together over three distinct time zones, stretching from Peking, China to San Diego, California and finally to me right outside of Washington, D.C, where thanks to a strong internet connection we discussed the ups and downs of ultrashort echo time (UTE) imaging. UTE is a method for direct imaging of tissues that have short transverse relaxation times by shortening the delay between excitation and readout. For example, in this paper, the echo time for UTE imaging was only 8 μs, compared to a traditional gradient echo readout, that would have a minimum of 2-5 ms, depending on the sequence. Jun and Jiang, along with their colleagues in the U.S. and China, have been working to apply UTE sequences to explore the T1 properties of cortical bone and give clinically relevant information on components of the cortical bone structures not easily investigated with conventional radiological techniques.

By |June 19th, 2017|Highlights-post, Highlights-QA|Comments Off on Q&A with Jun Chen and Jiang Du

June Highlights

June Cover Art

Accelerated MRI of the fetal heart using compressed sensing and metric optimized gating, by Christopher W.  Roy, Mike Seed and Christopher K. Macgowan

June Editor’s Picks

Measurement of bound and pore water T1 relaxation times in cortical bone using three-dimensional ultrashort echo time cones sequences, by Jun Chen, Eric Y. Chang, Michael Carl, Yajun Ma, Hongda Shao, Bimin Chen, Zhihong Wu and Jiang Du


Impact of transcytolemmal water exchange on estimates of tissue microstructural properties derived from diffusion MRI, by Hua Li, Xiaoyu Jiang, Jingping Xie, John C. Gore and Junzhong Xu


By |June 2nd, 2017|Highlights-post|Comments Off on June Highlights

Q&A with Kelly McPhee and Alan Wilman

                                                                            By Atef Badji and Nikola Stikov

Alan Wilman (Left) and Kelly McPhee (Right)

Among the Editor’s picks for May comes a paper from the department of Physics at the University of Alberta in Edmonton, Canada. In their work entitled ‘Transverse relaxation and flip angle mapping: Evaluation of simultaneous and independent methods using multiple spin echoes’, Kelly McPhee and Alan Wilman evaluated transverse relaxation (T2) and flip angle maps derived from Bloch simulations and Extended Phase Graphs (EPG). We conducted this interview with Kelly on a beautiful Sunday afternoon at the Honolulu convention center during the annual ISMRM meeting.

By |May 26th, 2017|Highlights-post, Highlights-QA|Comments Off on Q&A with Kelly McPhee and Alan Wilman